CZC24832 - CAS 1159824-67-5
Catalog number: 1159824-67-5
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C15H17FN6O2S
Molecular Weight:
364.399
COA:
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Targets:
PI3K
Description:
CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.
Purity:
0.98
Appearance:
Solid powder
Synonyms:
CZC24832; CZC-24832; CZC 24832
MSDS:
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InChIKey:
RXRZPHQBTHQXSV-UHFFFAOYSA-N
InChI:
InChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20)
Canonical SMILES:
CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
Current Developer:
Cellzome Ltd.
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CAS 1159824-67-5 CZC24832

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