|Description||Cysteamine has been shown to increase intracellular glutathione levels in cystinotic cells, thus restoring the altered redox state of the cells.|
TC-O9311 is a potent, selective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139) with no activity against a range of 90 diverse targets.
Naproxcinod, a nitro compound, has been found to be a nitric oxide donor as well as a cyclooxygenase inhibitor that was once studied aginast duchenne muscular d...
Omeprazole sulphone is the major metabolite of omeprazole, which is the gastric proton pump inhibitor. It is produced by cytochrome P450 (CYP)3A4 sulfoxidation ...
Enprofylline, a xanthine derivative, is a a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine rec...
Bisegliptin is an antidiabetic agent, but no detailed information has been published yet.
Tinyatoxin is a neurotoxin, acting via vanilloid receptors of sensory nerves.
Paquinimod, also known as ABR‑215757, belonging to the class of quinoline-3-carboxamide derivatives, is a S100A9 inhibitor. Paquinimod is an immunomodulatory co...
Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation a...
20-O-Acetylingenol-3-angelate is a natural compound extracted from Euphorbia conspicua N. E. Br. It is used as molluscicidal agent, anti-cancer agent and cytost...
O4I1 is a potent inducer of Oct3/4. O4I1 enhanced Oct3/4 expression. O4I1 not only promoted expression and stabilization of Oct3/4 but also enhanced its transcr...
Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma.
HLM 006474 acts as an E2F transcription factor inhibitor, preventing DNA binding activity. This results in the induction of apoptosis in breast cancer cells.
Atomoxetine is a norepinephrine reuptake inhibitor approved for the treatment of attention deficit hyperactivity disorder (ADHD).
Speract, a peptide associated with eggs of sea urchin, Lytechinus pictus, regulates sperm motility, also stimulates sperm mitochondrial metabolism.
Calyculin A is a effective inhibitor of the catalytic subunit of type-2A phosphatase as well as the type-1 phosphatase. IC50: 0.5 to 1 nM and 2 nM,respectively....
TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base form. There is no formal name yet, we temporally call this molecule as TPT-2...
Formononetin is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.
Arg-Gly-Glu-Ser, a RGD-related peptide, is a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets.
Antitumor Compound 1
Antitumor Compound 1 is a potent compound which comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.
Hexa-His, consisting of 6 His residues in a row, called His-Tag, is used as a metal binding site for the recombinant protein. His-Tag sequence can be placed on ...