|Targets||Others (Nonspecific immune stimulation) | DNA Alkylator/Crosslinker|
|Description||Low-dose preferentially deplets Treg cells; An alkylating agent of the nitrogen mustard type with antineoplastic and immunosuppressive activities; Phase I–II|
|Brife Description||Low-dose preferentially deplets Treg cells; An alkylating agent of the nitrogen mustard type with antineoplastic and immunosuppressive activities; Phase I–II|
|Appearance||Fine White lyophilised solid|
|Synonyms||Cytoxan; Clafen; Neosar; CTX; 2-Bis(2-chloroethyl)aminotetrahydro-2H-1,3,2-oxazophosphorine-2-oxide; N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide|
|Solubility||In water, 1-5 g/100 mL at 23 °C; slightly soluble in benzene, carbon tetrachloride; very slightly soluble in ether and acetone.|
|Storage||Stored at room temp or within 6 days if stored under refrigeration. When constituted with sterile water for injection or paraben-preserved bacteriostatic water for injection to a concn of 21 mg/ml, <1.5% cyclophosphamide decomposition will occur within 8|
|Application||Broad-spectrum antineoplastic agents. Cyclophosphamide can be used in the treatment of leukemia and other cancers.|
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