Cyclopamine - CAS 4449-51-8
Catalog number:
4449-51-8
Category:
Stem Cell Molecule
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H41NO2
Molecular Weight:
411.62
COA:
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Description:
Cyclopamine is a steroid alkaloid isolated from the corn lily (Veratrum californicum) and originally identified as a teratogenic agent. Cyclopamine has since been identified as a specific inhibitor of hedgehog singaling by direct binding to the heptahelical bundle of Smoothened. Hedgehog signaling is involved in embryogenesis as well as cancer progression. Cycoplamine has been utilized as a small molecule inducer of stem cell differentiation towards definitive endoderm pancreatic islet cells, as a modulator of cell proliferation, and as an anticancer drug.
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Purity:
0.98
Appearance:
White crystalline solid or clear solid film at bottom of vial
MSDS:
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Application:
Differentiation
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Chemical Structure

CAS 4449-51-8 Cyclopamine

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