CX-6258 hydrochloride hydrate - CAS 1353858-99-7
Catalog number:
1353858-99-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H27Cl2N3O4
Molecular Weight:
516.42
COA:
Inquire
Targets:
Pim
Description:
The hydrochloride hydrate salt form of CX-6258, a pan-Pim kinases inhibitor, has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. It has already been discontinued for Solid tumours. IC50: 5 n
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Purity:
98%
Appearance:
Powder
Synonyms:
C26H24ClN3O3.ClH.H2O; 2121AH; HY-18095A; CS-1530; W-6143
Solubility:
100 mM in DMSO (warmed),100 mM in H2O (warmed)
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
The hydrochloride hydrate salt form of CX-6258 is a pan-Pim kinases inhibitor that has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. It has already been discontinued for Solid tumours. IC5
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
ZOZTWDKBSOVPDP-LLDDCTHSSA-N
InChI:
InChI=1S/C26H24ClN3O3.ClH.H2O/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31;;/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31);1H;1H2/b22-16+
Canonical SMILES:
CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)C=C4C5=C(C=CC(=C5)Cl)NC4=O.O.Cl
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