|Description||CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation.|
|Appearance||white solid powder|
|Synonyms||CX-5461; CX 5461; CX5461.|
|Current Developer||Cylene Pharmaceuticals.|
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