Curcumenol - CAS 19431-84-6
Catalog number: 19431-84-6
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Chemical Family:
Curcumenol, one of the major components of Zedoary turmeric oil, has been widely used to treat cancer and inflammation.
Publictions citing BOC Sciences Products
  • >> More
3,8-dimethyl-5-(1-methylethylidene)-,(3S,3aS,6R,8aS)-; 6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro-; (3S,3aS,6R,8aS)-3,8-dimethyl-5-(propan-2-ylidene)-1,2,3,4,5,8a-hexahydro-6H-3a,6-epoxyazulen-6-ol; 3,8-dimethyl-5-(1-methylethylidene)-1,2,3,4,5,8a-hexahydro-6H-3a,6-epoxyazulen-6-ol
Quality Standard:
Enterprise Standard
1.Analysis of volatile components in Curcuma rhizome by microemulsion electrokinetic chromatography.
Yang FQ;Yang J;Zhang XM;Xu P;Xia ZN J Chromatogr Sci. 2013 Feb;51(2):155-60. doi: 10.1093/chromsci/bms120. Epub 2012 Jul 23.
Volatile chemicals are a group of very important compounds in natural products. Curcuma rhizome, which contains many bioactive volatile compounds, is a traditional Chinese medicine that has long been used for the treatment of several diseases. In the present study, a microemulsion electrokinetic chromatography (MEEKC) method was developed for the analysis of four volatile components in Curcuma rhizome, including germacrone, furanodiene, curcumenol and curdione. Experimental parameters, including the pH, type and concentrations of background electrolyte, and microemulsion compositions (type and concentrations of surfactant, co-surfactant and oil phase) were intensively investigated. Finally, the primary compounds in the methanol extract of Curcuma rhizome were separated within 30 min using a running buffer composed of 2.31% w/v (80 mmol/L) sodium dodecyl sulfate (SDS), 0.91% w/v (80 mmol/L) 1-octane, 6.95% w/v (937.5 mmol/L) 1-butanol and 1.
2.Phytochemical analysis and analgesic properties of Curcuma zedoaria grown in Brazil.
Navarro Dde F;de Souza MM;Neto RA;Golin V;Niero R;Yunes RA;Delle Monache F;Cechinel Filho V Phytomedicine. 2002 Jul;9(5):427-32.
The present study describes the phytochemical analysis and analgesic activity of Curcuma zedoaria rhizomes grown in Brazil. The results showed that the hydroalcoholic extract, fractions, specially dichloromethane, and a pure compound, denoted as curcumenol (1), exhibited potent and dose-related analgesic activity when evaluated in several models of pain in mice, including writhing, formalin and capsaicin. Compound (1), which seems to be the main active principle from this plant, presented promising analgesic effects, being several times more potent than different reference drugs evaluated in the same experimental models. The calculated ID50 values (micromol/kg, i.p) were 22 and 12 when evaluated in writhing and capsaicin tests, respectively, and 29 micromol/kg in relation to the second phase of the formalin model. The lack of effect in the hot plate test suggests that (1) act by a mechanism which do not involves the participation of the opioid system.
3.Fractionation of volatile constituents from curcuma rhizome by preparative gas chromatography.
Yang FQ;Wang HK;Chen H;Chen JD;Xia ZN J Autom Methods Manag Chem. 2011;2011:942467. doi: 10.1155/2011/942467. Epub 2011 Aug 18.
A preparative gas chromatography (pGC) method was developed for the separation of volatile components from the methanol extract of Curcuma rhizome. The compounds were separated on a stainless steel column packed with 10% OV-101 (3 m × 6 mm, i.d.), and then, the effluent was split into two gas flows. One percent of the effluent passed to the flame ionization detector (FID) for detection and the remaining 99% were directed to the fraction collector. Five volatile compounds were collected from the methanol extract of Curcuma rhizome (5 g/mL) after 83 single injections (20 uL) with the yield of 5.1-46.2 mg. Furthermore, the structures of the obtained compounds were identified as β-elemene, curzerene, curzerenone, curcumenol, and curcumenone by MS and NMR spectra, respectively.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Sesquiterpenoids Products

CAS 1529775-08-3 Guajadial F

Guajadial F
(CAS: 1529775-08-3)

Guajadial F is a sesquiterpenoid-based meroterpenoid isolated from the leaves of Psidium guajava. Guajadial F has potential anticancer effects. Biochemical topo...

CAS 929881-46-9 Cucumegastigmane I

Cucumegastigmane I
(CAS: 929881-46-9)

Cucumegastigmane I is a natural sesquiterpenoid isolated from the fruits of Trichosanthes kirilowii Maxim.

CAS 915289-60-0 Bakkenolide IIIa

Bakkenolide IIIa
(CAS: 915289-60-0)

Bakkenolide IIIa is extracted from the rhizomes of Petasites formosanus. Study shows that it protects from cerebral damage via inhibiting NF-κB activation.

CAS 13476-25-0 Linderane

(CAS: 13476-25-0)

Linderane was characterized as a mechanism-based inactivator of CYP2C9.

CAS 82442-48-6 Arteannuin A

Arteannuin A
(CAS: 82442-48-6)

Arteannuin A is isolated from Artemisia annua.

CAS 1394156-45-6 8α-Hydroxyhirsutinolide

(CAS: 1394156-45-6)

8α-Hydroxyhirsutinolide is isolated from the flowers of Vernonia cinerea. 8α-Hydroxyhirsutinolide was shown to inhibit TNF-α-induced NF-κB activity with the IC5...

CAS 16982-01-7 Iso-cuparenal

(CAS: 16982-01-7)

Iso-cuparenal is isolated from the herbs of Lepidozia reptans.

CAS 1748-81-8 Carabrone

(CAS: 1748-81-8)

Carabrone, isolated from the herbs of Carpesium abrotanoides, displays cytotoxic, antibacterial and antitumor activity. It also exhibited antifungal activities ...

CAS 34169-69-2 Pterosin Z

Pterosin Z
(CAS: 34169-69-2)

Pterosin Z is a natural sesquiterpenoid isolated from the rhizoma of Cibotium barometz (L.) J.Sm, the compound has smooth muscle relaxant activity.

(CAS: 7727-79-9)

Zederone isolated from the rhizomes of Curcuma zedoaria. It induces liver enlargement with scattered white foci over the organ.

CAS 30890-35-8 8-Epixanthatin

(CAS: 30890-35-8)

8-Epixanthatin is a light-induced growth inhibitor that can regulate the phototropic curvature in sunflower (Helianthus annuus) hypocotyls.

CAS 1829580-18-8 Dibritannilactone B

Dibritannilactone B
(CAS: 1829580-18-8)

Dibritannilactone B is isolated from the aerial parts of Inula britannica.

CAS 109770-86-7 8β-(4-Acetoxy-5-hydroxytigloyloxy)costunolide

(CAS: 109770-86-7)

8β-(4-Acetoxy-5-hydroxytigloyloxy)costunolide is isolated from the aerial parts of Artemisia myriantha.

(CAS: 6750-10-3)

Fuegin is a natural sesquiterpenoid found in the herbs of Polygonum hydropiper.

CAS 38230-99-8 Chloroenhydrin

(CAS: 38230-99-8)

Enhydrin chlorohydrin is a natural sesquiterpenoid found in the herbs of Smallanthus sonchifolius.

CAS 37239-48-8 Wilfortrine

(CAS: 37239-48-8)

Wilfortrine is a natural compound of the sesquiterpenoid class found in the roots of Tripterygium wilfordii Hook. f. Wilfortrine exhibits an inhibitory effect o...

CAS 104975-02-2 3-Acetoxy-4,7(11)-cadinadien-8-one

(CAS: 104975-02-2)

3-Acetoxy-4,7(11)-cadinadien-8-one isolated from the herbs of Eupatorium adenophorum.

CAS 442851-27-6 Methyl isodrimeninol

Methyl isodrimeninol
(CAS: 442851-27-6)

Methyl isodrimeninol isolated from the herbs of Polygonum flaccidum Meissn.

CAS 40716-66-3 Nerolidol

(CAS: 40716-66-3)

Nerolidol is a natural compound.

CAS 349112-30-7 Cryptomeridiol 11-rhamnoside

Cryptomeridiol 11-rhamnoside
(CAS: 349112-30-7)

Cryptomeridiol 11-rhamnoside is a natural sesquiterpenoid found in branch of Eucalyptus globulus Labill.

Chemical Structure

CAS 19431-84-6 Curcumenol

Quick Inquiry

Verification code

Featured Items