|Description||cUMP-AM is a membrane-permeant and metabolically activatable prodrug of cUMP, the potential further second messenger. cUMP is released after permeation and metabolism by esterases, which is trapped inside the cell and metabolized to result in a pulse-type signal.|
|Purity||≥ 95% by HPLC for mixtures of isomers|
|Synonyms||Uridine- 3', 5'- cyclic monophosphate, acetoxymethyl ester|
c-(Ap-8-Br-Gp) is an analogue of c-(ApGp), the potential bacterial second messenger, which is used for binding studies and as precursor for further modification...
8-ABA-cAMP is a selective cAMP analogue oreferring site B of R I of cAMP-dependent protein kinase. It is used as a ligand in affinity chromatography and can be ...
Sp-2-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatogra...
2'-APNC-cAMP is an analogue of cAMP with higher solubility in water, which can be used as a ligand in affinity chromatography and be modified with fluorophores ...
2'-dcAMP is an analogue of cAMP, which is a protein kinase A inactive agent.
c[G(2',5')pS-A(3',5')pS], isomer 1 and i
(CAS: 1638242-56-4 / 1638243-00-1)
c[G(2',5')pS-A(3',5')pS] is an isomeric di-thiophosphate analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is resistant a...
8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptos...
8-pCPT-cGMP is a selective activator of cGMP-dependent protein kinase type I α and type II, as well as of cGMP-gated ion channels. It has higher membrane permea...
Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases.
Sp-2'-AEC-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chroma...
Rp-2-Cl-cAMPS is an analogue of Rp-cAMPS, the protein kinase A inhibitor. The chlorine atom in position 2 of adenine nucleobase significantly increase the stabi...
8,8'-Di-Br-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used for binding studies and for further modifications with spacers o...
c-diAMP was recognized as a second messenger for signalling DNA integrity in Bacillus subtilisduring sporulation, and an additional purine-based signalling nucl...
DMACM-caged 8-Br-cGMP is a fluorescent precursor of 8-bromo cyclic cGMP. 8-Br-cGMP and a fluorescent coumarin analogue are released by irradiation. It is much m...
Rp-8-CPT-cAMPS is an analog of Rp-cAMPS and a competitive inhibitor of protein kinase A type I and II (cAMP antagonist). It effects against mammalian cyclic nuc...
2'-O-MS-cGMP is a cGMP analogue, which is used for coupling of ligands including proteins for ELISA.
2'-ADOC-cAMP is a cAMP analogue with increased solubility, which is often used as a ligand in affinity chromatography and can be modified with fluorophores or o...
2'-AEC-cGMP-Agarose is the protein kinase G activator cGMP immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography...