|Description||cUMP-AM is a membrane-permeant and metabolically activatable prodrug of cUMP, the potential further second messenger. cUMP is released after permeation and metabolism by esterases, which is trapped inside the cell and metabolized to result in a pulse-type signal.|
|Purity||≥ 95% by HPLC for mixtures of isomers|
|Synonyms||Uridine- 3', 5'- cyclic monophosphate, acetoxymethyl ester|
8-pCPT-2'-O-Me-cAMP is a PDE-stable activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has hig...
4-N3-PET-8-Biotin-11-cGMP is a cGMP analogue used for photoaffinity labelling of cGMP-responsive receptors.
Sp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and...
Sp-2'-AHC-cAMPS-Agarose is the PDE-resistant protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in a...
8-AET-cGMP is a ligand in affinity chromatography and can be modified with fluorophores or other markers.
2'-AHC-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling...
Sp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chrom...
Sp-2-AHA-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and ot...
Sp-cAMPS, sodium salt
Sp-cAMPS is an activator of protein kinase A (cAMP agonist). It exhibits high resistance against cyclic nucleotide phosphodiesterases and membrane permeability ...
c-diIMP is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which is potentially used as an adjuvant for mucosal vaccination.
Sp-8-OH-cAMPS is a polar analogue of Sp-cAMPS, the protein kinase A activator, with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiest...
c-(Ap-8-AET-Gp) is an analogue of messenger c-(ApGp), the bacterial second, which is used as a ligand for affinity chromatography or for coupling of labelling s...
8-MA-cAMP is a selective cAMP analogue that has affinity to site B of protein kinase A type I and II. Site A activity is developed when 8-MA-cAMP acts synergist...
8-OH-cAMP is a polar analogue of cAMP used for the study of extracellular cAMP receptors. When applied by patch clamp techniques, 8-OH-cAMP remains trapped insi...
2'-O-MS-cGMP is a cGMP analogue, which is used for coupling of ligands including proteins for ELISA.
8-AET-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activ...