|Description||Crotonic acid can induce histone modifications in chemically induced pluripotent stem cells (CiPSCs).|
|Synonyms||(E)-but-2-enoic acid; but-2-enoic acid; trans-2-Butenoic acid|
Pifithrin-β hydrobromide is a cell-permeable and reversible inhibitor of p53-dependent apoptosis and transcription. It was shown to suppress self-renewal of emb...
Cyclopamine is a steroid alkaloid isolated from the corn lily (Veratrum californicum) and originally identified as a teratogenic agent. Cyclopamine has since be...
AR-A014418 is an ATP-competitive inhibitor of glycogen synthase kinase 3β (GSK-3β). It was shown to promote osteogenic differentiation of human adipose-derived ...
O-Phospho-L-serine is an agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM). It was shown to induce neuronal differen...
BMS 493 is a pan-retinoic acid receptor (pan-RAR) inverse agonist.
Geldanamycin is a benzoquinone ansamycin antibiotic that inhibits heat shock protein 90 (HSP90). Geldanamycin has been shown to promote survival of neural stem ...
CHF 5074 is a novel γ-secretase modulator. It reduces Aβ42 and Aβ40 secretion with IC50 values of 3.6 and 18.4 μM respectively. It protects SH-SY5Y human neuron...