Crolibulin - CAS 1000852-17-4
Catalog number: 1000852-17-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
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Description:
Crolibulin, also known as EPC2407 and crinobulin,  is a small molecule tubulin polymerization inhibitor with potential antineoplastic activity. Microtubulin inhibitor EPC2407 binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of tubulin into microtubules, which may result in cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. As a vascular disruption agent (VDA), this agent also disrupts tumor neovascularization, which may result in a reduction in tumor blood flow and tumor hypoxia and ischemic necrosis.
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Appearance:
Solid powder
Synonyms:
EPC2407; EPC 2407; EPC-2407; Crolibulin, crinobulin.
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Current Developer:
EpiCept Corporation.
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CAS 1000852-17-4 Crolibulin

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