|Description||CRANAD 2, a difluoroboron-derivatized curcumins, is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. It penetrates the blood-brain barrier and shows a high affinity for Abeta aggregates (K(d) = 38.0 nM).|
|Brife Description||Near-infrared probe that detects Aβ40 aggregates|
|Synonyms||[4-[2-[6-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-2,2-difluoro-1,3-dioxa-2-boranuidacyclohex-5-en-4-ylidene]ethylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium; CRANAD-2; AOB1744; ZINC215806197; CRANAD 2|
|Solubility||Soluble to 5 mM in DMSO with gentle warming|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -35℃ for long term (months to years).|
|Application||Implicated in Alzheimer's disease|
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