CP 461 - CAS 227619-96-7
Catalog number: 227619-96-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C25H22ClFN2O
Molecular Weight:
420.91
COA:
Inquire
Targets:
Phosphodiesterase (PDE)
Description:
CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2.
Purity:
>98%
Appearance:
Solid powder
Synonyms:
CP 461; CP-461; CP461; OSI 461; UNII-68OJX9I7DT. N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide;hydrochloride; CAS: 227619-92-3 (CP-461 free base);
MSDS:
Inquire
InChIKey:
KGXPDNOBLLACKL-UHFFFAOYSA-N
InChI:
1S/C25H21FN2O.ClH/c1-17-22(13-18-9-11-27-12-10-18)21-8-7-20(26)14-24(21)23(17)15-25(29)28-16-19-5-3-2-4-6-19;/h2-14H,15-16H2,1H3,(H,28,29);1H
Canonical SMILES:
CC1=C(C2=C(C1=CC3=CC=NC=C3)C=CC(=C2)F)CC(=O)NCC4=CC=CC=C4.Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Phosphodiesterase (PDE) Products


CAS 939055-18-2 FIPI

FIPI
(CAS: 939055-18-2)

FIPI, a derivative of halopemide, is a potent and selective phospholipase D (PLD) inhibitor with IC50 values of 20 and 25 nM for PLD2 and PLD1 respectively. It ...

CAS 225100-12-9 PDE IV-IN-1

PDE IV-IN-1
(CAS: 225100-12-9)

An inhibitor of phosphodiesterase IV with potential for the treatment of asthma, COPD or other inflammatory diseases.

CAS 794568-92-6 BAY 73-6691

BAY 73-6691
(CAS: 794568-92-6)

BAY 73-6691 is a phosphodiesterase inhibitor selective for the PDE9A subtype under the development of Bayer. It selectively inhibits human PDE9 with IC50 value ...

CAS 1229652-21-4 HA-130

HA-130
(CAS: 1229652-21-4)

HA-130, an effective autotaxin (ATX) inhibitor, has been found to restrain the cell migration related to ATX in in an A2058 melanoma cells. IC50: 28 nM.

CAS 334827-98-4 Gisadenafil besylate

Gisadenafil besylate
(CAS: 334827-98-4)

Gisadenafil besylate is a potent PDE5 inhibitor (IC50 = 1.23 nM) with >100-fold selectivity for PDE5 over PDE6. Gisadenafil besylate inhibits the breakdown of c...

CAS 50847-11-5 Ibudilast

Ibudilast
(CAS: 50847-11-5)

Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barri...

CAS 119615-63-3 Olprinone Hydrochloride

Olprinone Hydrochloride
(CAS: 119615-63-3)

Olprinone is a selective phosphodiesterase 3 (PDE3) inhibitor. Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinon...

CAS 58-32-2 Dipyridamole

Dipyridamole
(CAS: 58-32-2)

Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.

Quick Inquiry

Verification code

Featured Items