CP-457920 - CAS 220860-50-4
Catalog number: 220860-50-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H17N3O3
Molecular Weight:
323.35
COA:
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Targets:
GABA Receptor
Description:
CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the treatment of Vascular dementia but discontinued.
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
N-benzyl-6-ethoxy-4-oxo-1H-1,5-naphthyridine-3-carboxamide; CP-457920; CP457920; CP 457920; UNII-13BME2F602; CP-457,920
MSDS:
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InChIKey:
DGFVZQGXKQCQGK-UHFFFAOYSA-N
InChI:
1S/C18H17N3O3/c1-2-24-15-9-8-14-16(21-15)17(22)13(11-19-14)18(23)20-10-12-6-4-3-5-7-12/h3-9,11H,2,10H2,1H3,(H,19,22)(H,20,23)
Canonical SMILES:
CCOC1=NC2=C(C=C1)NC=C(C2=O)C(=O)NCC3=CC=CC=C3
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