copanlisib hydrochloride - CAS 1402152-13-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H30Cl2N8O4
Molecular Weight:
553.445
COA:
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Targets:
PI3K
Description:
Copanlisib hydrochloride is a potent inhibitor of Class I phosphoinositide 3-kinase which showed a therapeutic effect on non-Hodgkin lymphoma. It was approved to treat follicular lymphoma that has relapsed after treatment with at least two other anticancer therapies.
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Brife Description:
inhibitor of Class I phosphoinositide 3-kinase
Related CAS:
1032568-63-0 (free base)
Synonyms:
Aliqopa; Copanlisib dihydrochloride; UNII-03ZI7RZ52O; 03ZI7RZ52O; BAY 80-6946 dihydrochloride; BAY-80-6946 dihydrochloride
MSDS:
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Application:
the potential treatment of non-Hodgkin lymphoma
InChIKey:
STGQPVQAAFJJFX-UHFFFAOYSA-N
InChI:
InChI=1S/C23H28N8O4.2ClH/c1-33-19-17(35-10-2-6-30-8-11-34-12-9-30)4-3-16-18(19)28-23(31-7-5-25-20(16)31)29-21(32)15-13-26-22(24)27-14-15;;/h3-4,13-14H,2,5-12H2,1H3,(H2,24,26,27)(H,28,29,32);2*1H
Canonical SMILES:
COC1=C(C=CC2=C1N=C(N3C2=NCC3)NC(=O)C4=CN=C(N=C4)N)OCCCN5CCOCC5.Cl.Cl
Current Developer:
Bayer
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