|Targets||Amyloid-β | γ-secretase|
|Description||Compound W, also called 3,5-bis(4-Nitrophenoxy)benzoic acid, a 3,3'-diiodothyronine sulfate cross-reactive substance, is an inhibitor of γ-secretase which causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).|
|Brife Description||Reduces Aβ42 levels; γ-secretase inhibitor|
|Synonyms||3,5-bis(4-Nitrophenoxy)benzoic acid; 173550-33-9; gamma-Secretase Modulator, CW; ACMC-1CUIP; SCHEMBL264541; CHEMBL1553155; CTK8B1007; JOSXKPZXMVHRKU-UHFFFAOYSA-; DTXSID10587892; JOSXKPZXMVHRKU-UHFFFAOYSA-N; HMS3269J17; ZINC2576957; ANW-22664; MFCD02093450; AKOS015833412; 3,5-bis (4-nitrophenoxy) benzoic acid; NCGC00167814-01; AJ-42568; AK-63150; EN002659; OR182673; KB-234083; TR-007681; B2120; Compound W|CW|3,5-Bis(4-nitrophenoxy)benzoic acid; BRD-K98143539-001-01-4; I14-62910|
|Solubility||Soluble to 100 mM in DMSO, to 5 mM in ethanol, and to 5 mM in 1.1eq. NaOH.|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -23℃ for long term (months to years).|
|Melting Point||577.655℃ at 760 mmHg|
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