|Description||Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demonstrable antineoplastic activity (inhibit IMR32 (neuroblastoma): IC50= 2.16nM, Hs746T (gastric carcinoma) IC50=5.20nM, CFPAC-1 (pancreatic carcinoma)IC50=3.46nM, and MCF-7 (breast cancer)IC50=18.47nM|
|Brife Description||Inhibits tubulin polymerization (IC50= 2.2 μM)|
|Synonyms||2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol; 1-(3,4,5-trimethoxyphenyl)-2-(3'-hydroxy-4'-methoxyphenyl)ethene; D-64131; 74588-78-6; (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE; CHEMBL140220; C16H13NO2; (5-methoxy-1H-indol-2-yl)-phenylmethanone; (5-Methoxy-1H-indol-2-yl)(phenyl)methanone; (5-Methoxy-1H-indol-2-yl)-phenyl-methanone; NCGC00025243-01; Tocris-1643; AC1N0QCR; 2-Benzoyl-5-methoxyindole; SCHEMBL5828518; CTK8F8930; DTXSID30397970; ICMIJSRDISNKOC-UHFFFAOYSA-N; HMS3268K07; ZINC2526466; 3570AH; BDBM50107658; AKOS022507157; CS-1008; 2-BENZOYL-5-METHOXY-1H-INDOLE; NCGC00025243-02; AN-25376; HE053371; HE187776; HY-15482; LS-83224; QC-11710; AB0165802; KB-208742; D64131; W-5310; BRD-K26997899-001-01-4; D-64131|(5-Methoxy-1H-indol-2-yl)phenylmethanone|
|Solubility||Soluble to 100 mM in ethanol and to 100 mM in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -53℃ for long term (months to years).|
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