Combretastatin A4 - CAS 117048-59-6
Category: ADCs
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Molecular Formula:
C18H20O5
Molecular Weight:
316.35
COA:
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Tag:
ADCs Cytotoxin
Description:
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demonstrable antineoplastic activity (inhibit IMR32 (neuroblastoma): IC50= 2.16nM, Hs746T (gastric ca
Purity:
≥95%
Appearance:
Soild powder
Synonyms:
2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol; 1-(3,4,5-trimethoxyphenyl)-2-(3'-hydroxy-4'-methoxyphenyl)ethene;
MSDS:
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InChIKey:
HVXBOLULGPECHP-WAYWQWQTSA-N
InChI:
InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-
Canonical SMILES:
COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)O
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Chemical Structure

CAS 117048-59-6 Combretastatin A4

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