|Description||Columbianadin was found to possess strong inhibitory activity against the inflammatory response of IL-1β-treated A549 cells and LPS-treated MH-S cells. Columbianadin was found to inhibit NO production by down-regulation of inducible NO synthase. Moreover, columbianadin was also proved to possess significant inhibitory activity against LPS-induced lung inflammation following oral administration at a dose of 20-60 mg/kg. Columbianadin can be a potential new agent for treating inflammatory lung disorders.|
|Synonyms||(S)-8-[1-[(Z)-2-Methyl-2-butenoyloxy]-1-methylethyl]-8,9-dihydro-2H-furo[2,3-h]-1-benzopyran-2-one; Columbianadin; ColuMbianin; ZosiMin; Columbianetin angelate|
Psoralidin isolated from the seeds of Psoralea corylifolia. It inhibits phosphatidylinositol 3-kinase activation and transcriptionally.
Heraclenol 3'-O-glucoside isolated from the herbs of Heracleum repula Franch.
Imperatorin isolated from the root of Angelica dahurica Benth. et Hook. It can suppress multidrug-resistant human liver cancer growth in vivo by inducing Mcl-1...
Auraptenol is a natural coumarin found in the fruits of Citrus aurantium, it has antifibrotic activity and the anti-hyperalgesic action which may be as a novel ...
Moluccanin diacetate is isolated from the herbs of Croton cascarilloides.
Isosaxalin is from the roots of Angelica polymorpha Maxim.
Source from roots of Peucedanum praeruptorum Dunn.
7'-O-Ethylmarmin is a natural coumarin isolated from the herbs of Citrus maxima.
(-)-Praeruptorin B is a natural coumarin compound found in some plant.
Hydrangetin is a coumarin isolated from the rhizome of Daphne papyracea var. crassiuscula.
7-Geranyloxy-5-methoxycoumarin can be found in the twigs of Toddalia asiatica.
Source from fruits of Citrus medica L. Isobergapten was identified as the principal constituents responsible for the antimycobacterial activity of the roots of ...
8-(6-Hydroperoxy-3,7-dimethylocta-2,7-dienyloxy)psoralen is a natural coumarin isolated from Psoralea corylifolia L
Lansiumarin A is a coumarin compound isolated from Clausena lansium (wampee).
Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) ...
Praeruptorin C (Pra-C) has been widely used as an antioxidant and a calcium antagonist to treat diseases. Pra-C partially protects cortical neurons by inhibitin...
Dicumarol is a natural chemical used as an anticoagulant agents that functions as a vitamin K antagonist and is also a derivative of Coumarin (C755380).
Coumarin, which is found in the herbs of Melilotus officinalis, is used in the pharmaceutical industry as a precursor reagent in the synthesis of a number of sy...
Hydramicromelin B is a coumarin isolated from the aerial parts of Micromelum integerrimum.