Co 101244 hydrochloride - CAS 193356-17-1
Catalog number: 193356-17-1
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C21H27NO3.HCl
Molecular Weight:
377.91
COA:
Inquire
Targets:
NMDA Receptor
Description:
Co 101244 hydrochloride, with strongly neuroprotective effect in vivo and in vitro, is an ifenprodil-like noncompetitive, highly selective antagonist of NR2B-containing NMDA receptors (IC5= 43 nM).
Purity:
>98%
Appearance:
White Solid
Synonyms:
1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol;hydrochloride; 4-hydroxy-N-(2-(4-hydroxyphenoxy)ethyl)-4-(4-methylbenzyl)piperidine; Co 101244; 193359-26-1 (Co 101244 free base); Co-101244; Co101244;PD 174494; PD-174494; PD174494
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
MSDS:
Inquire
Melting Point:
131-133℃
InChIKey:
WFFZHKKSIDENAJ-UHFFFAOYSA-N
InChI:
1S/C21H27NO3.ClH/c1-17-2-4-18(5-3-17)16-21(24)10-12-22(13-11-21)14-15-25-20-8-6-19(23)7-9-20;/h2-9,23-24H,10-16H2,1H3;1H
Canonical SMILES:
CC1=CC=C(C=C1)CC2(CCN(CC2)CCOC3=CC=C(C=C3)O)O.Cl
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