CNX-1351 - CAS 1276105-89-5
Catalog number:
1276105-89-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
Inquire
Targets:
PI3K
Description:
CNX-1351 is a selective covalent Inhibitor of PI3Kα. In an end point assay, CNX-1351 potently inhibited PI3Kα and was 20−400 times less potent against β, γ, and δ. CNX-1351 inhibit PI3Kα signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX-1351 inhibits growth of cells dependent on PI3Kα. CNX-1351 also inhibits PI3Kα signaling in vivo and bonds to p110α.
Publictions citing BOC Sciences Products
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Purity:
0.98
Appearance:
solid powder
Synonyms:
CNX-1351; CNX 1351; CNX1351.
MSDS:
Inquire
Current Developer:
Celgene Avilomics Research.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1276105-89-5 CNX-1351

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