|Description||CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DAMGO-induced desensitization and internalization of μ-opioid receptors.|
|Appearance||Off White solid|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
BMS 214428 has antineoplastic effect.
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