|Description||Clozapine is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia.|
|Synonyms||HF 1854, LX 100-129|
Remoxipride is a selective dopamine D2 receptor antagonist. It shows selectivity over D3 and D4 receptors with Ki values are ~ 300nM for D2 receptor, ~ 1600nM f...
ST-836, a dopamine receptor ligand, might have similar effect with dopamine and probably useful as an antiparkinsonian agent.
Fluphenazine decanoate dihydrochloride
Fluphenazine is a potent antipsychotic that acts by inhibiting dopamine receptors (Ki values 0.2 nM, 0.11 nM, and 2.0nM for D2, D3, and 5-HT2 receptors, respect...
6,7-Dimethoxy-2-Aminotetraline hydrobromide is a dopamine receptor agonist.
SKF 83959 hydrobromide
SKF 83959 hydrobromide is a dopamine D1-like receptor partial agonist (Ki = 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors, respectively), exhib...
Sonepiprazole is a selective, brain penetrating and orally bioactive antagonist for the rat and human dopamine D4 receptor (Ki = 10 nM) with low affinity at oth...
RU 24213 is a dopamine D2 receptor agonist as well as a kappa opioid receptor antagonist.
The hydrochloride salt form of Ziprasidone which is an antagonism of both serotonin and dopamine receptor and could be effective against schizophrenia.
Thiethylperazine is a dopamine receptor antagonist It is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it ...
Pramipexole (Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
Quinagolide hydrochloride is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor.
NPEC-caged-dopamine is a caged version of dopamine. It can release dopamine leading to dopamine D1 receptor activation upon UV light illumination.
A potent and selective dopamine (DA) D2 receptor agonist.
PD 128907 is a selective D2 and D3 dopamine receptor agonist that can be used as an antipsychotic.
Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist like other atypical antipsychotic agents. Ziprasidone targets dopamine neurotransmis...
SKF 38393 hydrobromide
SKF 38393 hydrobromide is a selective dopamine D1-like receptor partial agonist (Ki = 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors,...
Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
A dopamine receptor agonist.
Sumanirole maleate, also referred as PNU 95666E or U95666E, is a high affinity D2 receptor full agonist that shows >200-fold selectivity over dopamine receptor ...
Quinelorane hydrochloride, 2-aminopyridine analog of quinpirole, is a dopamine D2 and D3 receptor agonist (Ki= 5.7 and 3.4 nM respectively).