|Description||Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.|
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and ...
Alverine Citrate is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.
Perphenazine is a typical antipsychotic. a piperazinyl phenothiazine, used to treat psychosis
The tosylate salt form of Lumateperone which is an highly effective antagonist of 5-HT2A receptor, could be used against insomnia. IC50: 0.54 nM(Ki).
SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other recept...
BMS 181101, an indole derivative, has been found to be a 5-HT receptor agonist that could be probably effective against depression and also restrain serotonin r...
TG6-10-1, a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2, has been shown antagonist activity at human EP2 receptor expressed in...
Tertatolol, a benzothiopyran derivative, is a potent dual antagonist of beta-adrenoceptor and 5-HT receptor, with antihypertensive effect.
Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.
Sarizotan, also known as EMD-128130, is a full 5-HT1a agonist and a dopamine D2-like agonist/partial agonist used in clinical trials for the treatment of l-dopa...
Lasmiditan is a high-affinity, highly selective 5-HT1F receptor agonist(Ki=2.1 nM) for the treatment of acute migraine.
Ondansetron Hydrochloride Dihydrate
Ondansetron hydrochloride dihydrate is a specific and competitive antagonist of serotonin 5-HT3 receptor (Ki = 0.77 nM) with anxiolytic and neuroleptic activiti...
Cyclobenzaprine HCl is a muscle relaxant, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the sp...
Bromperidol, a derivative of butyrophenone, is an antipsychotic commonly used in the treatment of schizophrenia as it could bind to the D2 dopamine and 5-HT2A s...
The hydrochloride salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome.
Thesuccinate salt form of Frovatriptan, a carbazole derivative, has been found to be a 5-HT receptor agonist that could be used as an antimigraine agent.
Rupatadine, with the potential to treat allergic rhinitis and urticaria, is a potent and long-lasting dual antagonist of PAF/H1. in vitro: Without affecting con...
Naratriptan is a triptan agent that is used for the treatment of migraine headaches.
Flibanserin, a benzimidazole derivative, has been found to be a Serotonin 1A/2A receptor agonist that was once studied as antidepressant as well as anxiolytic a...