Clomifene citrate - CAS 50-41-9
Catalog number: B0084-300308
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H28ClNO.C6H8O7
Molecular Weight:
598.08
COA:
Inquire
Targets:
Estrogen Receptor/ERR
Description:
Clomifene Citrate is a selective estrogen receptor modulator used in the treatment of ovulation induction. It is used to treat breast cancer for its antineoplastic activity.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-300308 50 g $299 In stock
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Brife Description:
estrogen receptor modulator, breast cancer
Purity:
>98%
Synonyms:
NSC 35770; CLOMIPHENE CITRATE; Zuclomiphene citrate; Clomivid; Clomphid
MSDS:
Inquire
Application:
the treatment of breast cancer
InChIKey:
PYTMYKVIJXPNBD-OQKDUQJOSA-N
InChI:
InChI=1S/C26H28ClNO.C6H8O7/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,3-4,19-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;
Canonical SMILES:
CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
1.Clomiphene citrate before and after withdrawal bleeding for induction of ovulation in women with polycystic ovary syndrome: Randomized cross-over trial.
Elbohoty AE1, Amer M1, Abdelmoaz M1. J Obstet Gynaecol Res. 2016 Apr 28. doi: 10.1111/jog.12996. [Epub ahead of print]
AIM: To compare the ovarian response to early versus late clomiphene citrate (CC) in women with polycystic ovary syndrome (PCOS).
2.Effect of Laparoscopic Ovarian Drilling on Outcomes of In Vitro Fertilization in Clomiphene-Resistant Women with Polycystic Ovary Syndrome.
Eftekhar M1, Deghani Firoozabadi R1, Khani P1, Ziaei Bideh E1, Forghani H2. Int J Fertil Steril. 2016 Apr-Jun;10(1):42-7. Epub 2016 Apr 5.
BACKGROUND: Recently the laparoscopic ovarian drilling (LOD) has been used as a surgical treatment for ovulation in women with polycystic ovarian syndrome (PCOS), although its mechanism and outcomes are still unclear. This study was undertaken to evaluate the in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) outcomes in clomiphene-resistant women with PCOS who were treated with LOD.
3.The effect of clomiphene citrate vs. letrozole on post-coital tests.
Check JH, Liss JR, Vaniver J. Clin Exp Obstet Gynecol. 2016;43(2):184-5.
PURPOSE: To determine if letrozole is less likely to create a hostile cervical mucus than clomiphene citrate.
4.Nitric oxide donors improve the ovulation and pregnancy rates in anovulatory women with polycystic ovary syndrome treated with clomiphene citrate: A RCT.
Mahran A1, Abdelmeged A1, Shawki H1, Moheyelden A1, Ahmed AM2. Int J Reprod Biomed (Yazd). 2016 Jan;14(1):9-14.
BACKGROUND: Clomiphene citrate (CC) is the first line agent used for ovulation induction in patients with polycystic ovarian syndrome (PCOS). However, there is marked discrepancy between the ovulation and pregnancy rates achieved, which may be attributed to the undesirable effect of CC on cervical mucus and endometrium.
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CAS 50-41-9 Clomifene citrate

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