Clidinium Bromide - CAS 3485-62-9
Catalog number: 3485-62-9
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
Clidinium bromide is an anticholinergic used as an antispasmodic to reduce stomach acid and decreases intestinal spasms.
White Solid
(1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide;
Soluble in DMSO
Store at -20 °C
An anticholinergic. Used as an antispasmodic.
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Melting Point:
Canonical SMILES:
Current Developer:
1.Evaluation of the benefit of addition of clidinium C to a Helicobacter pylori eradication regimen.
Chorami M1, Zojaji H1, Naderi N1, Moghimi-Dehkordi B2, Mirsattari D1, Shalmani HM1. Gastroenterol Hepatol Bed Bench. 2013 Summer;6(3):141-5.
AIM: This study aimed to evaluate the success of H.pylori eradication therapy in patients with dyspepsia by therapeutics regimes with and without clidinium C.
2.Stability-indicating HPLC method for simultaneous determination of clidinium bromide and chlordiazepoxide in combined dosage forms.
Pathak A1, Rai P, Rajput SJ. J Chromatogr Sci. 2010 Mar;48(3):235-9.
The study describes development and subsequent validation of a stability indicating reverse-phase high-performance liquid chromatography method for the simultaneous estimation of clidinium bromide (CLI) and chlordiazepoxide (CHLOR) from their combination drug product. Chromatographic separations are performed at ambient temperature on a Phenomenex Luna C(18) (250 mm x 4.6 mm, i.d., 5 microm) column using a mobile phase consisting of potassium dihydrogen phosphate buffer (0.05 M, pH 4.0 adjusted with 0.5% orthophosphoric acid)-methanol- acetonitrile (40:40:20, v/v/v). The flow rate is 1.0 mL/min, and the detection wavelength is 220 nm. The method is validated with respect to linearity, precision, accuracy, system suitability, and robustness. The utility of the procedure is verified by its application to marketed formulations that were subjected to accelerated degradation studies. The method distinctly separated the drug and degradation products even in actual samples.
3.Simultaneous Determination of Clidinium Bromide and Chlordiazepoxide in Combined Dosage Forms by High-Performance Liquid Chromatography.
Ashour S1, Kattan N1. J Pharm (Cairo). 2013;2013:417682. doi: 10.1155/2013/417682. Epub 2013 Feb 24.
A sensitive and precise RP-HPLC method has been developed for the simultaneous estimation of clidinium bromide (CDB) and chlordiazepoxide (CDZ) in pure and pharmaceutical formulations. The separation was achieved on a Nucleodur C8 (250 × 4.6 mm i.d., 5 μm particle size) column at 25°C. CH3CN-MeOH-NH4OAc 0.1M (30 : 40 : 30, v/v/v) was used as the mobile phase at a flow rate of 1.0 mL min(-1) and detector wavelength at 218 nm. Almotriptan (ALT) was used as internal standard. The validation of the proposed method was carried out for linearity, accuracy, precision, LOD, LOQ, and robustness. The method showed good linearity in the ranges of 2.5-300.0 and 3.0-500.0 μg mL(-1) for CDB and CDZ, respectively. The percentage recovery obtained for CDB and CDZ was 100.40-103.38 and 99.98-105.59%, respectively. LOD and LOQ were 0.088 and 0.294 μg mL(-1) for CDB and 0.121 and 0.403 μg mL(-1) for CDZ, respectively. The proposed method was successfully applied to the determination of CDB and CDZ in combined dosage forms and the results tallied well with the label claim.
4.Imaging left ventricular muscarinic receptor heterogeneity: a tool to evaluate individuals at risk for sudden death?
Caldwell JH, Link JM. Circ Cardiovasc Imaging. 2009 Sep;2(5):353-5. doi: 10.1161/CIRCIMAGING.109.900621.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related mAChR Products

CAS 1859081-58-5 PF-06767832

(CAS: 1859081-58-5)

PF-06767832 is a cell permeable, potent and selective M1 muscarinic acetylcholine receptor Positive Allosteric Modulator (PAM).

CAS 131986-45-3 Xanomeline

(CAS: 131986-45-3)

Xanomeline is a Muscarinic M1 and M4 receptor agonist under the development of Eli Lilly, though it is also known to act as a M5 receptor antagonist. Xanomeline...

CAS 62-51-1 Methacholine chloride

Methacholine chloride
(CAS: 62-51-1)

Methacholine chloride, a synthetic choline ester, is pharmaceutical agent acting as a β2-adrenergic agonist used in the treatment of pulmonary and respiratory d...

CAS 145-13-1 Pregnenolone

(CAS: 145-13-1)

Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor- and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively.

CAS 101-31-5 Hyoscyamine

(CAS: 101-31-5)

Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.

CAS 1235-82-1 Biperiden Hydrochloride

Biperiden Hydrochloride
(CAS: 1235-82-1)

Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkin...

CAS 10405-02-4 Trospium chloride

Trospium chloride
(CAS: 10405-02-4)

Trospium chloride is a competitive muscarinic cholinergic receptor antagonist.

CAS 1135242-13-5 VU 0357017 hydrochloride

VU 0357017 hydrochloride
(CAS: 1135242-13-5)

The hydrochloride salt form of VU0357017 which is a selective M1 agonists and has been found to be probably effective in the treatment of hippocampal-dependent ...

Chemical Structure

CAS 3485-62-9 Clidinium Bromide

Quick Inquiry

Verification code

Featured Items