Clemastine fumarate - CAS 14976-57-9
Catalog number:
Molecular Formula:
Molecular Weight:
Publictions citing BOC Sciences Products
  • >> More
>98 %
White or off-white crystalline power
Quality Standard:
1. Antihistamines in the Treatment of Atopic Dermatitis
Sari M. Herman and Ronald B. Vender. Journal of Cutaneous Medicine and Surgery Volume 7 Number 6 December 2003
In much the same way, studies investigating the efficacy of clemastine fumarate, a classic antihistamine, were shown to have contradictory results as no significant antipruritic effect was established in one study conducted by Wahlgreen et al. while another study showed considerable improvement. Cyproheptadine HCl, a serotonin and histamine antagonist with sedative activity, showed improvement in two studies. Baraf compared the antipruritic effect of cyproheptadine HCl to hydroxyzine HCl and demonstrated a reduction in the degree of pruritus but a more significant relief of itching by use of hydroxyzine. Klein and Galant’s comparison of cyproheptadine to hydroxyzine similarly suggested that hydroxyzine was a more effective antihistamine than cyproheptadine in relieving itching associated with AD in children. Lack of a placebo control group made it difficult to determine the actual therapeutic benefit in this study.
2. The Microbiology and Management of Acute and Chronic Rhinosinusitis
James A. Hadley. Current Infectious Disease Reports 2001, 3:209–216
The anticholiergic properties of the first-generation anti-histamines may reduce the rhinorrhea associated with the inflammation, but the drying effects of these products thicken sinus secretions and possibly slow mucociliary clearance. Clemastine fumarate prescribed for volunteers with viral head colds reduced sneezing and rhinorrhea. The newer second-generation antihistamines (acrivastine, cetirizine, fexofenadine, and loratadine) would be favored in patients with an allergic history. The topical antihistamines (azelastine, levocobastine) are extremely potent histamine blockers, but no controlled studies of their use in rhinosinusitis are available at this time.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products

CAS 134-85-0 Cetirizine Impurity (4-Chlorobenzophenone)

Cetirizine Impurity (4-Chlorobenzophenon
(CAS: 134-85-0)

4-Chlorobenzophenone, is a building block used in various chemical synthesis. It can be used for the preparation of a variety of functionalized Coumarin derivat...

CAS 5339-62-8 fast red GTR base

fast red GTR base
(CAS: 5339-62-8)

CAS 59767-24-7 Clemastine Fumarate Impurity C

Clemastine Fumarate Impurity C
(CAS: 59767-24-7)

1-(4-Chlorophenyl)-1-phenylethanol is used in the synthetic preparation of rhodium-catalyzed arylation of nitriles, ketones and imines with tetrafluoroborate or...

Chemical Structure

CAS 14976-57-9 Clemastine fumarate

Quick Inquiry

Verification code

Featured Items