Clazosentan - CAS 180384-56-9
Catalog number: 180384-56-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H23N9O6S
Molecular Weight:
577.57
COA:
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Targets:
Endothelin Receptor
Description:
Clazosentan, also called as AXV 034, Ro 61-1790 or VML 588, a novel endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain injury. In 2016 Actelion plans two phase III trials of Clazosentan for Cerebral vasospasm (in patients with aneurysmal subarachnoid haemorrhage) in Japan.
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Purity:
95%
Appearance:
White solid
Synonyms:
N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamide AXV 034 AXV 343434 AXV-034 AXV-034343 AXV-343434 AXV343434 clazosentan Ro 61-1790 Ro-61-1790 VML 588 VML-588 VML588
MSDS:
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Quantity:
Data not available, please inquire.
Boiling Point:
754.5ºC at 760 mmHg
Density:
1.485 g/cm3
InChIKey:
LFWCJABOXHSRGC-UHFFFAOYSA-N
InChI:
1S/C25H23N9O6S/c1-15-7-8-20(27-14-15)41(36,37)32-24-21(40-19-6-4-3-5-18(19)38-2)25(39-12-11-35)29-22(28-24)16-9-10-26-17(13-16)23-30-33-34-31-23/h3-10,13-14,35H,11-12H2,1-2H3,(H,28,29,32)(H,30,31,33,34)
Canonical SMILES:
CC1=CN=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=CC(=NC=C3)C4=NNN=N4)OCCO)OC5=CC=CC=C5OC
Current Developer:
Actelion Pharmaceuticals
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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Chemical Structure

CAS 180384-56-9 Clazosentan

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