CKD-516 HCl - CAS 1188371-47-2
Catalog number: 1188371-47-2
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C26H29ClN6O5S
Molecular Weight:
573.07
COA:
Inquire
Targets:
Microtubule/Tubulin
Description:
This active molecular is a tubulin polymerisation inhibitor which is applicated for solid cancer treatment. CKD-516 disruptes tubulin of the endothelial cytoskeleton selectively. In Jun 2012, a South Korea company, Chong Kun Dang initiated enrolment in a phase I trial for solid tumours treatment in South Korea. In Dec 2014, Phase-I clinical trials in Solid tumours in South Korea was on going.
Purity:
98%
Appearance:
Powder
Synonyms:
CKD-516 HCl; CKD 516 HCl; CKD516 HCl; (2S)-2-amino-3-methyl-N-[4-[3-(1,2,4-triazol-1-yl)-4-(3,4,5-trimethoxybenzoyl)phenyl]-1,3-thiazol-2-yl]butanamide;hydrochloride;1188371-47-2 (free base)
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Solid tumours
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
FIAUXCMEQTWLQZ-FTBISJDPSA-N
InChI:
InChI=1S/C26H28N6O5S.ClH/c1-14(2)22(27)25(34)31-26-30-18(11-38-26)15-6-7-17(19(8-15)32-13-28-12-29-32)23(33)16-9-20(35-3)24(37-5)21(10-16)36-4;/h6-14,22H,27H2,1-5H3,(H,30,31,34);1H/t22-;/m0./s1
Canonical SMILES:
CC(C)C(C(=O)NC1=NC(=CS1)C2=CC(=C(C=C2)C(=O)C3=CC(=C(C(=C3)OC)OC)OC)N4C=NC=N4)N.Cl
Current Developer:
Originator: Chong Kun Dang
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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