|Description||CK 17 is a interleukin-1 antagonist. It can suppress fibroblast proliferation.|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
guselkumab is a selectively blocking agent for interleukin-23 (IL-23), a cytokine involved in plaque psoriasis. guselkumab was approved by FDA as an anti-inflam...
Tyrphostin A1, can be as a negative control for inhibition of EGFR (IC50 >1250 µM) and was shown to inhibit the tyrosine phosphorylation of IL-2 stimulated Tyk-...
SC144 is an orally active small-molecule gp130 inhibitor (C50 = 0.72 μM).
Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.
Ginsenoside Rg5, a main constituent isolated from red ginseng, exhibits anti-inflammatory property as in LPS-stimulated alveolar macrophages it inhibited the ex...
BMS-279700, belonging to a family of novel anilino 5-azaimidazoquinoxaline analogues, is an orally active lead candidate that blocks the production of proinflam...
Reslizumab is a humanized monoclonal antibody resistant to interleukin-5 (IL-5). It is approved for additional maintenance treatment of patients with severe ast...
IL5 receptor antagonist
Beta-mangostin, a natural product extracted from the fruits of Garcinia mangostana, can reduced the levels of TNF-α and IL-1β in peritoneal fluid.
Veledimex S enantiomer
Veledimex S enantiomer is the S enantiomer of veledimex which is an orally active small molecule diacylhydrazine and controls the expression of the target gene.
Ladarixin is Interleukin 8A and Interleukin 8B receptor antagonist. IL-8A and IL-8B inhibition blocks and reverses type 1 diabetes in mice. In Dec 2015, Phase-I...
CK 17 is a interleukin-1 antagonist. It can suppress fibroblast proliferation.
Veledimex racemate is the racemate of veledimex. Veledimex is an orally active small molecule diacylhydrazine and controls the expression of the target gene.
CK-119, a dihydropyridazino-pyridazine compound, is a potent IL-1 blocker to inhibit cell growth of fibroblast-like corneal and conjunctival cells mainly throug...
APY0201, an effective IL-12/23 inhibitor, has been found to have potential useful in treatment of inflammation. IC50: 5.2 nM .
GIBH-130 is an effective inhibitor of neuroinflammation. GIBH-130 significantly suppresses theIL-1βsecretion by activated microglia (IC50=3.4 nM). GIBH-13 const...
Pentagalloylglucose, a polyphenol isolated from the fruits of Pistacia lentiscus, increases a population of Treg cells in conjunction with Treg-inducing factors...