CK-119 - CAS 197917-10-5
Catalog number: 197917-10-5
Category: Inhibitor
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Molecular Formula:
C21H23ClN4O5
Molecular Weight:
446.88
COA:
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Targets:
Interleukin Related
Description:
CK-119, a dihydropyridazino-pyridazine compound, is a potent IL-1 blocker to inhibit cell growth of fibroblast-like corneal and conjunctival cells mainly through the inhibition of DNA and RNA syntheses but not protein synthesis.
Purity:
>98%
Appearance:
Solid powder
Synonyms:
diethyl 6-[(4-chlorophenyl)methyl]-1,4-dimethyl-5-oxopyridazino[4,5-c]pyridazine-3,4-dicarboxylate; CK-119; CK119; CK 119; UNII-AL53N923EI; GC-6119; GC 6119; GC6119
MSDS:
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Boiling Point:
277.4ºC at 760 mmHg
Density:
1.16 g/cm3
InChIKey:
FVWILZZSXZMAHY-UHFFFAOYSA-N
InChI:
1S/C21H23ClN4O5/c1-5-30-19(28)17-21(3,20(29)31-6-2)16-15(25(4)24-17)11-23-26(18(16)27)12-13-7-9-14(22)10-8-13/h7-11H,5-6,12H2,1-4H3
Canonical SMILES:
CCOC(=O)C1=NN(C2=C(C1(C)C(=O)OCC)C(=O)N(N=C2)CC3=CC=C(C=C3)Cl)C
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CAS 197917-10-5 CK-119

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