CITCO - CAS 338404-52-7
Catalog number: 338404-52-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H12Cl3N3OS
Molecular Weight:
436.74
COA:
Inquire
Targets:
Constitutive androstane receptor
Description:
CITCO is a constitutive androstane receptor (CAR) agonist (EC50 = 49 nM), inducing nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes, including several cytochrome P450 isoforms.
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Purity:
≥98%
Appearance:
White solid to Pale orange solid
Synonyms:
(E)-1-[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]-N-[(3,4-dichlorophenyl)methoxy]methanimine;6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Constitutive androstane receptor (CAR) agonist.
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
ZQWBOKJVVYNKTL-AUEPDCJTSA-N
InChI:
1S/C19H12Cl3N3OS/c20-14-4-2-13(3-5-14)18-17(25-7-8-27-19(25)24-18)10-23-26-11-12-1-6-15(21)16(22)9-12/h1-10H,11H2/b23-10+
Canonical SMILES:
C1=CC(=CC=C1C2=C(N3C=CSC3=N2)C=NOCC4=CC(=C(C=C4)Cl)Cl)Cl
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Chemical Structure

CAS 338404-52-7 CITCO

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