|COA||Certificate of Analysis-Cilengitide (TFA salt) 188968-51-6 B17LM09012|
|Description||Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. It is being studied for the treatment of glioblastoma.|
|Brife Description||cyclic Arg-Gly-Asp peptide, potential antineoplastic activity|
|Synonyms||Cilengitide TFA salt; EMD-121974; Cilengitide [USAN:INN]; UNII-4EDF46E4GI; EMD-12192|
|Application||the potential treatment of glioblastoma|
|Shelf Life||2 years|
|Current Developer||Technical University Munich / Merck KGaA|
Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.
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