CI-1002 hydrochloride - CAS 149062-75-9
Catalog number: 149062-75-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C13H15Cl3N2
Molecular Weight:
305.63
COA:
Inquire
Targets:
AChE
Description:
The hydrochloride salt form of CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction in Alzheimer's disease.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
UNII-I77CZ53Y9M; PharmaGSID_47259; 149062-75-9; 1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino(2,1-b)quinazoline hydrochloride; CI-1002 hydrochloride; 1,3-dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline hydrochloride
Storage:
Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
Inquire
Quality Standard:
In-house standard
Quantity:
Milligram-Grams
InChIKey:
KPVQNWQDBLOUQW-UHFFFAOYSA-N
InChI:
InChI=1S/C13H14Cl2N2.ClH/c14-9-6-11(15)10-8-17-5-3-1-2-4-13(17)16-12(10)7-9;/h6-7H,1-5,8H2;1H
Canonical SMILES:
C1CCC2=NC3=CC(=CC(=C3CN2CC1)Cl)Cl.Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related AChE Products


CAS 13473-38-6 Pipenzolate

Pipenzolate
(CAS: 13473-38-6)

Pipenzolate, a muscarinic receptor antagonist, commonly existed as bromide salt form and could be used as a spasmolytic and could probably effective in aid ther...

CAS 102518-79-6 (-)-Huperzine A (HupA)

(-)-Huperzine A (HupA)
(CAS: 102518-79-6)

(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G...

CAS 149062-75-9 CI-1002 hydrochloride

CI-1002 hydrochloride
(CAS: 149062-75-9)

The hydrochloride salt form of CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effectiv...

CAS 1953-04-4 Galanthamine HBr

Galanthamine HBr
(CAS: 1953-04-4)

Galanthamine is an AChE inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase.

CAS 115-79-7 Ambenonium dichloride

Ambenonium dichloride
(CAS: 115-79-7)

Ambenonium dichloride is an extremely selective, potent and rapidly reversible inhibitor of acetylcholinesterase (AChE) with IC50 value of 0.000698 μM. It is us...

CAS 1225-55-4 Protriptyline hydrochloride

Protriptyline hydrochloride
(CAS: 1225-55-4)

The hydrochloride salt of Protriptyline which is a norepinephrine uptake blocker that could be effective as an antidepressant.

CAS 510-77-0 Galanthaminone

Galanthaminone
(CAS: 510-77-0)

Galantamine is a competitive and reversible cholinesterase(AChE) inhibitor, which is used for the treatment of mild to moderate Alzheimer's disease and various ...

CAS 129101-54-8 Rivastigmine Tartrate

Rivastigmine Tartrate
(CAS: 129101-54-8)

Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to mod...

CAS 1684-40-8 Tacrine hydrochloride

Tacrine hydrochloride
(CAS: 1684-40-8)

Tacrine hydrochloride is a potent cholinesterase inhibitor used for the treatment of memory deficits in patients with Alzheimers's disease. Tacrine hydrochlorid...

CAS 1192750-33-6 PE 154

PE 154
(CAS: 1192750-33-6)

PE 154 is a fluorescent inhibitor of both AChE and BChE with IC50 values of 280 pM and 16 nM. PE 154 targets and labels β-amyloid plaques in histochemical analy...

CAS 548-66-3 Drofenine hydrochloride

Drofenine hydrochloride
(CAS: 548-66-3)

Drofenine hydrochloride is a widely used anticholinergic acts on smooth muscle to stop muscle spasms.

CAS 209394-46-7 Ladostigil tartrate

Ladostigil tartrate
(CAS: 209394-46-7)

Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer’s disease. Ladostigil is...

CAS 120786-18-7 (±)-Huperzine A

(±)-Huperzine A
(CAS: 120786-18-7)

Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholin...

Icopezil maleate
(CAS: 145815-98-1)

The maleate salt form of Icopezil, a benzoxazol derivative, has been found to be an acetylcholinesterase inhibitor and was once studied for the treatment of Alz...

CAS 116-38-1 Edrophonium chloride

Edrophonium chloride
(CAS: 116-38-1)

Edrophonium chloride is a reversible Acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine compe...

CAS 1912399-75-7 BT-11

BT-11
(CAS: 1912399-75-7)

BT-11, the extract of dried root of Polygala tenuifolia Willdenow, is an orally available LANCL2 binding compound for treating inflammatory bowel disease. In ad...

CAS 51-60-5 Neostigmine Methylsulfate

Neostigmine Methylsulfate
(CAS: 51-60-5)

Neostigmine methyl sulfate is a cholinesterase inhibitor used in the treatment of myasthenia gravis, can not cross the blood-brain barrier.

CAS 120014-06-4 Donepezil

Donepezil
(CAS: 120014-06-4)

Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to se...

Neostigmine Iodide
(CAS: 1212-37-9)

This active molecular is a reversible acetylcholinesterase inhibitor as a parasympathomimetic compound under the development of Flamel Technologies. Neostigmine...

CI 1002
(CAS: 149028-28-4)

CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction...

Chemical Structure

CAS 149062-75-9 CI-1002 hydrochloride

Quick Inquiry

Verification code

Featured Items