Chlorquinaldol - CAS 72-80-0
Catalog number: 72-80-0
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C10H7Cl2NO
Molecular Weight:
228.07
COA:
Inquire
Targets:
Antibacterial
Description:
Chlorquinaldol is an antimicrobial agent.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Synonyms:
BM-14190, SKF 105517
MSDS:
Inquire
1.A comparative study of novel spectrophotometric resolution techniques applied for pharmaceutical mixtures with partially or severely overlapped spectra.
Lotfy HM1, Tawakkol SM2, Fahmy NM3, Shehata MA1. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt B:937-52. doi: 10.1016/j.saa.2014.09.117. Epub 2014 Oct 12.
Simultaneous determination of mixtures of lidocaine hydrochloride (LH), flucortolone pivalate (FCP), in presence of chlorquinaldol (CQ) without prior separation steps was applied using either successive or progressive resolution techniques. According to the concentration of CQ the extent of overlapping changed so it can be eliminated from the mixture to get the binary mixture of LH and FCP using ratio subtraction method for partially overlapped spectra or constant value via amplitude difference followed by ratio subtraction or constant center followed by spectrum subtraction spectrum subtraction for severely overlapped spectra. Successive ratio subtraction was coupled with extended ratio subtraction, constant multiplication, derivative subtraction coupled constant multiplication, and spectrum subtraction can be applied for the analysis of partially overlapped spectra. On the other hand severely overlapped spectra can be analyzed by constant center and the novel methods namely differential dual wavelength (D(1) DWL) for CQ, ratio difference and differential derivative ratio (D(1) DR) for FCP, while LH was determined by applying constant value via amplitude difference followed by successive ratio subtraction, and successive derivative subtraction.
2.Therapeutic use of topical corticosteroids in the vesiculobullous lesions of incontinentia pigmenti.
Kaya TI1, Tursen U, Ikizoglu G. Clin Exp Dermatol. 2009 Dec;34(8):e611-3. doi: 10.1111/j.1365-2230.2009.03301.x. Epub 2009 Jun 1.
Incontinentia pigmenti (IP) is a rare genodermatosis caused by a mutation of nuclear factor kappa B essential modulator gene. There is no specific treatment for IP, therefore it has been claimed that there is no effective treatment to hasten resolution of any of the phases of IP. However, the initial vesiculobullous stage of IP is characterized histopathologically by eosinophilic inflammation, which is expected to respond to corticosteroids. An 18-day-old female neonate was seen, with vesicles on her trunk and limbs diagnosed as the vesiculobullous stage of IP. The patient was treated with a double-compound cream containing a potent corticosteroid (difluocortolone valerate 0.1%) and an antiseptic (chlorquinaldol 1%), to be applied to the lesions twice daily. Five days later, resolution of the lesions was almost complete. As chlorquinaldol has no known anti-inflammatory activity, we attribute this improvement to difluocortolone valerate. This case shows that early lesions of IP with eosinophilic inflammation are treatable.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Antibacterial Products


CAS 73384-59-5 Ceftriaxone

Ceftriaxone
(CAS: 73384-59-5)

Ceftriaxone is an antibiotic useful for the treatment of a number of bacterial infections. It inhibits bacterial cell wall synthesis by means of binding to the ...

CAS 38821-53-3 Cephradine

Cephradine
(CAS: 38821-53-3)

Cephradine is abroad spectrum first generation cephalosporin antibiotic.

CAS 3671-08-7 chlortetracycline hydrochloride (1:x)

chlortetracycline hydrochloride (1:x)
(CAS: 3671-08-7)

Chlortetracycline HCl is the first identified tetracycline antibiotic.

CAS 32986-56-4 Tobramycin

Tobramycin
(CAS: 32986-56-4)

Tobramycin is an aminoglycoside antibiotic with an IC50 of 9.7 μM.

CAS 153-61-7 Cephalothin

Cephalothin
(CAS: 153-61-7)

Cephalothin, one of the first generation cephalosporin antibiotic, has been found to be probably effective in some respiratory diseases and neuromuscular juncti...

CAS 10592-13-9 Doxycycline HCl

Doxycycline HCl
(CAS: 10592-13-9)

Doxycycline HCl is a tetracycline antibiotic that commonly used to treat a variety of infections and MMP inhibitor.

CAS 252260-02-9 Posizolid

Posizolid
(CAS: 252260-02-9)

Posizolid is an oxazolidinone antibiotic that had been in phase II clinical trials for the treatment of tuberculosis but was discontinued.

CAS 26787-78-0 Amoxicillin

Amoxicillin
(CAS: 26787-78-0)

Amoxicillin is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually th...

CAS 121123-17-9 Cefprozil monohydrate

Cefprozil monohydrate
(CAS: 121123-17-9)

Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic. Cefprozil hydrate (Cefzil) can be used to treat bronchitis, ear infections, ski...

CAS 173903-47-4 Tizoxanide

Tizoxanide
(CAS: 173903-47-4)

Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosp...

CAS 34604-60-9 5-hydroxypyrazine-2-carboxylic acid

5-hydroxypyrazine-2-carboxylic acid
(CAS: 34604-60-9)

A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide.

CAS 27164-46-1 Cefazolin sodium

Cefazolin sodium
(CAS: 27164-46-1)

Cefazolin sodium, derived from 7-amino-cephalosporanic acid, is a semi-synthetic, first-generation cephalosporin antibiotic.

CAS 52-51-7 Bronopol

Bronopol
(CAS: 52-51-7)

Bronopol is an organic compound that is used as an antimicrobial with low mammalian toxicity and high activity.

CAS 64-73-3 Demeclocycline HCl

Demeclocycline HCl
(CAS: 64-73-3)

Demeclocycline HCl is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.

Kasugamycin hydrochloride hydrate
(CAS: 200132-83-8)

Kasugamycin, an aminoglycosidic antibiotic, inhibits protein synthesis by interacting with the 30S ribosomal subunit. The mechanism of inhibition of protein syn...

RNPA1000
(CAS: 359600-10-5)

RNPA1000 isa RnpA inhibitor as an attractive antimicrobial development candidate.

CAS 79-57-2 Oxytetracycline

Oxytetracycline
(CAS: 79-57-2)

Oxytetracycline (Terramycin) was the second of the broad-spectrum tetracycline group of antibiotics to be discovered.

CAS 116-43-8 Succinylsulfathiazole

Succinylsulfathiazole
(CAS: 116-43-8)

Succinylsulfathiazole, a sulfonamide derivative, could restrain the bacteria in the intestine to block the production of folic acid.

CAS 122-16-7 Sulfanitran

Sulfanitran
(CAS: 122-16-7)

Sulfanitran, a sulfonamide derivative, could be commonly used as an anticoccidial drug for animals.

CAS 62893-20-3 Cefoperazone Sodium

Cefoperazone Sodium
(CAS: 62893-20-3)

Cefoperazone Sodium is a third generation cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM, used in the treatment...

Chemical Structure

CAS 72-80-0 Chlorquinaldol

Quick Inquiry

Verification code

Featured Items