|Description||Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chlorotoxin binds to Cl– channels (small conductance epithelial chloride channels) in the brain and spinal cord and inhibits Cl– influx.|
|Purity||95 % (HPLC).|
|Appearance||White lyophilized solid|
|Solubility||well in water and saline.|
|Storage||stable in freeze-dried state. In solution, keep at -20 °C.|
organophosphoric inhibitor, SA-152, on the fibrinogen-coagulating and TAME-esterase activity of bovine α-thrombin.
A reversible myorelaxant and ganglioblocker Diterpenoid alkaloid Semi-Synthetic, from Methyllicoctonine isolated from Delphinium rotundifolium Afan. (Ranunculac...
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
Ganglioblocker Quaternary triethylamine derivative Synthetic
Synthetic., a GABA-gated chloride channel blocker, non-competitive GABA antagonist in mammals.
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
The lanthanide element from Glutaned replaces calcium in its complex with prothrombine,<br/>thus preventing the formation of thrombine and interrupting the bloo...