|Description||Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.|
10-Hydroxycamptothecin inhibits the growth of BT-20 and MDA-231 cell with IC50 of 34.3 nM and 7.27 nM, respectively, more potently than camptothecin (CPT) with ...
Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues. It is a family of tetrahydroisoquinoline alkaloids with wide r...
Atomoxetine is a norepinephrine reuptake inhibitor approved for the treatment of attention deficit hyperactivity disorder (ADHD).
Vadadustat is a potent Hypoxia-inducible factor-proline dioxygenase inhibitor, which leads to stabilization and increased levels of HIFα. It is used for the tre...
PFK15 is a potent and selective 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM.
Epiberberine, a natural bioactive alkaloid, has anti-adipogenic effect and is found to have potential effect in blocking cox-2 to get a chemopreventive property...
Lotilaner is an insecticide and veterinary drug.
Tetrahydrofolic acid is a folic acid derivative. It is a cofactor in many bio-reactions, especially in the metabolism of amino acids and nucleic acids.
2-Aminoheptane, a fatty Amine compound, is commonly used in proteomics research and could also be used to product some A3 adenosine receptor antagonists.
Diacetazotol, also referred to Pellidol, inhibits dioxin-induced ethoxyresorufin-O-deethylase (EROD) activity (IC50= 75±4 nM) and has been used in ointment or d...
HIF-2a Translation Inhibitor 76
A cell-permeable HIF-2a translation inhibitor (IC50 value 5 µM). It inhibits HIF-2a translation via enhancing the binding of IRP1 (Iron-Regulatory Protein 1) to...
D-Luciferin sodium salt
Sodium salt form of D-Luciferin, derived from the luciferase gene of photinus pyralis, is commonly used as a reporter gene for studying transcriptional regulati...
BMS-554417 is a novel inhibitor of IGF-IR, which inhibits IGF-IR and insulin receptor kinase activity and proliferation in vitro, with the IC50 for proliferatio...
Isovaleramide is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases.
Ginkgolic Acid is a natural compound with suspected cytotoxic, allergenic, mutagenic and carcinogenic properties.
BAY-876 is a potent and selective GLUT1 inhibitor (IC50 = 2 nM) with good stability in vitro and high bioavailability in vivo. BAY-876 can be used as an antican...
K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, w...
2(acute)-Deoxyguanosine is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that u...
Valrubicin (AD-32) is a chemotherapy drug used to treat bladder cancer. It is a semisynthetic analog of the anthracycline doxorubicin, and is administered by in...
Carotegrast is an anti-inflammatory agent as a Integrin alpha4 inhibitor.