|Description||Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.|
LM11A 31 dihydrochloride
LM11A-31 is a p75 neurotrophin receptor ligand that can inhibit nerve growth factor binding to p75NTR-F. It can prevent and reverse atrophy of cholinergic neuri...
BAY 678 is a cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM) that displays around 2000-fold selectivity for NHE over a panel of 21 other...
synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobi...
Atractylenolide III is a major component of Atractylodes rhizome, which can induce apoptosis of the lung carcinoma cells.
Taurocholic Acid Sodium Salt Hydrate
Choleretic; Its sodium salt is a bile salt formed in the liver by conjugation of cholic acid with taurine that is involved in the emulsification of lipids used ...
This active molecular is a selective and potent NK(3) antagonist. It has a high affinity for recombinant human (pK(i) value 8.9) and native guinea pig (pK(i) va...
The impurity of GC376 and a 3CLpro inhibitor
YK-4-279 is a potent inhibitor of EWS-FLI1 binding to RNA helicase A (RHA).YK-4-279 eliminates cyclin D levels by blocking the interaction of EWS-FLI1 with RHA ...
Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM,...
CP-664511 is a potent compound that is a alpha4beta1/vascular cell adhesion molecule-1 (VCAM-1) inhibitor which has therapeutic potential in treating allergic a...
Lubabegron is a β3-adrenoreceptor agonist.
Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion pr...
PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class.
Antiviral and antitumor agent.
GSK-1071306 is one of the metabolites of pazopanib which is a inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity as a approve...
Benserazide HCl is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
Bendamustine, a lbenzimidazol derivative, has been found to be an alkylating agent that acts through restraining DNA synthesis so that could be useful as an ant...
CL 43356 is a synthetic bio-active chemical.
Protease-Activated Receptor-4, a member of the PARs family, is activated by thrombin, trypsin and cathepsin G but also is the agonist o fproteinase-activated re...
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen and an RIA based on monoclonal antibody raised against this 8-amino-acid sequenc...