|Description||CHF-6162 is an agonist of glucocorticoid receptor (GR) (IC50 = 0.24nM), which shows greater potency than fluticasone and budesonide in a radioligand binding assay.|
|Brife Description||agonist of glucocorticoid receptor (GR), airway inflammation|
|Application||the potential teatment of airway inflammation|
Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
Ciclesonide, a glucocorticoid, could be useful in the treatment of sorts of airway inflammatory diseases like allergic rhinitis.
Loteprednol etabonate is an anti-inflammatory corticosteroid used in ophthalmology.
PF-04171327 is a dissociated agonist of the glucocorticoid receptor (DAGR), which is a selective high-affinity partial agonist of the GR. It has potent anti-inf...
Mometasone furoate, prodrug of the free form mometasone, is an agent with high affinity for the glucocorticoid receptor with anti-allergic property. It can be u...
Triamcinolone Acetonide is a long-acting synthetic and a more potent type of triamcinolone, about 8 times as effective as prednisone.
A glucocorticoid receptor modulator.
Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.
The acetate-protect form of Dexamethasone which is a glucocorticoid and could be used as a anti-inflammatory agent.
Ginsenoside Rg1 is extrected from the roots of Panax ginseng C. A. Mey. It has estrogen-like activity and should be classified as a novel class of potent phytoe...
Prednisolone Sodium Phosphate
The disodium phosphate salt form of Prednisolone which has anti-inflammatory and immunsuppressive effect for behaving as a glucocorticoid.
Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever...
Flumethasone pivalate is a topical glucocorticoid receptor agonist with anti-inflammatory, antipruritic and vasoconstrictive properties.
(+)-ZK 216348 is a selective nonsteroidal glucocorticoid receptor (GR) agonist for the treatment of experimental colitis (IC50 values of 20, 20, and 80 nM for G...
Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.
Amcinonide is a corticosteroid (IC50=3.38 nM) used as anti-inflammatory and antipruritic agents.
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It was also found to strongly potentia...
Betamethasone hydrochloride is the hydrochloride of betamethasone, which is a synthetic corticosteroid and agonist of glucocorticoid receptor. It does not cause...
Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone d...