|Description||CHF-6162 is an agonist of glucocorticoid receptor (GR) (IC50 = 0.24nM), which shows greater potency than fluticasone and budesonide in a radioligand binding assay.|
|Brife Description||agonist of glucocorticoid receptor (GR), airway inflammation|
|Application||the potential teatment of airway inflammation|
Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened he...
AL 082D06, also called as D-06, is a selective nonsteroidal antagonist of glucocorticoid receptor (GR) (Ki= 210 nM) without significant activity on AR, PR, MR a...
Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone d...
Betamethasone hydrochloride is the hydrochloride of betamethasone, which is a synthetic corticosteroid and agonist of glucocorticoid receptor. It does not cause...
Flunisolide is a corticosteroid and used for the treatment of allergic rhinitis.
Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
Glucocorticoid receptor agonist
Glucocorticoid receptor agonist is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties.
Ginsenoside Rg1 is extrected from the roots of Panax ginseng C. A. Mey. It has estrogen-like activity and should be classified as a novel class of potent phytoe...
Cortodoxone, a glucocorticoid receptor antagonist, is an intermediate which can be oxygenated to cortisol.
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It was also found to strongly potentia...
Prednisolone Sodium Phosphate
The disodium phosphate salt form of Prednisolone which has anti-inflammatory and immunsuppressive effect for behaving as a glucocorticoid.
Desonide is the generic name of a low potency topical corticosteroid that has been available since the 1970s. It is primarily used to treat atopic dermatitis (e...
Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.
Loteprednol etabonate is an anti-inflammatory corticosteroid used in ophthalmology.
Fluticasone furoate is a synthetic corticosteroid derived from fluticasone as a selective high affinity glucocorticoid agonist, MRP4 inhibitor;
GSK 9027 is a glucocorticoid receptor agonist (pIC50 = 8) inhibiting production of the proinflammatory mediator IL-6 in vivo. GSK 9027 is used for the treatment...
Budesonide is a glucocorticoid steroid that activates the glucorcorticoid receptor with an EC50 value of 12.4 nM. Like other glucocorticoids, budesonide reduces...
The acetate-protect form of Dexamethasone which is a glucocorticoid and could be used as a anti-inflammatory agent.
Meprednisone is a glucocorticoid and a methylated derivative of prednisone.
Mometasone furoate, prodrug of the free form mometasone, is an agent with high affinity for the glucocorticoid receptor with anti-allergic property. It can be u...