|Description||CHF-6162 is an agonist of glucocorticoid receptor (GR) (IC50 = 0.24nM), which shows greater potency than fluticasone and budesonide in a radioligand binding assay.|
|Brife Description||agonist of glucocorticoid receptor (GR), airway inflammation|
|Application||the potential teatment of airway inflammation|
Dexamethasone is a glucocorticoid with anti-inflammatory activity that reduces levels of activated NF-κB in immature dendritic cells (DCs) and inhibits differen...
Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone d...
Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.
Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
Loteprednol etabonate is an anti-inflammatory corticosteroid used in ophthalmology.
Budesonide is a glucocorticoid steroid that activates the glucorcorticoid receptor with an EC50 value of 12.4 nM. Like other glucocorticoids, budesonide reduces...
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It was also found to strongly potentia...
CHF-6162 is an agonist of glucocorticoid receptor (GR) (IC50 = 0.24nM), which shows greater potency than fluticasone and budesonide in a radioligand binding ass...
Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened he...
Fluticasone furoate is a synthetic corticosteroid derived from fluticasone as a selective high affinity glucocorticoid agonist, MRP4 inhibitor;
Ciclesonide, a glucocorticoid, could be useful in the treatment of sorts of airway inflammatory diseases like allergic rhinitis.
Meprednisone is a glucocorticoid and a methylated derivative of prednisone.
Triamcinolone Acetonide is a long-acting synthetic and a more potent type of triamcinolone, about 8 times as effective as prednisone.
Cortodoxone, a glucocorticoid receptor antagonist, is an intermediate which can be oxygenated to cortisol.
Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topic...
Ginsenoside Rg1 is extrected from the roots of Panax ginseng C. A. Mey. It has estrogen-like activity and should be classified as a novel class of potent phytoe...
Flunisolide, a kind of corticosteroid compound, often being used against allergic rhinitis by activating glucocorticoid receptors. It was also found that it mig...
Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
Prednisolone Sodium Phosphate
The disodium phosphate salt form of Prednisolone which has anti-inflammatory and immunsuppressive effect for behaving as a glucocorticoid.
Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.