|Description||CHF-6162 is an agonist of glucocorticoid receptor (GR) (IC50 = 0.24nM), which shows greater potency than fluticasone and budesonide in a radioligand binding assay.|
|Brife Description||agonist of glucocorticoid receptor (GR), airway inflammation|
|Synonyms||CHF-6162; CHF 6162; CHF6162|
|Application||the potential teatment of airway inflammation|
Mifepristone is a progesterone receptor antagonist(IC50= 0.2 nM) and a glucocorticoid receptor antagonist(IC50= 2.6 nM). It is used as an abortifacient in the f...
Triamcinolone Acetonide is a long-acting synthetic and a more potent type of triamcinolone, about 8 times as effective as prednisone.
Amcinonide is a corticosteroid (IC50=3.38 nM) used as anti-inflammatory and antipruritic agents.
Budesonide is a glucocorticoid steroid that activates the glucorcorticoid receptor with an EC50 value of 12.4 nM. Like other glucocorticoids, budesonide reduces...
CHF-6162 is an agonist of glucocorticoid receptor (GR) (IC50 = 0.24nM), which shows greater potency than fluticasone and budesonide in a radioligand binding ass...
Ciclesonide, a glucocorticoid, could be useful in the treatment of sorts of airway inflammatory diseases like allergic rhinitis.
Meprednisone is a glucocorticoid and a methylated derivative of prednisone.
Fluticasone furoate is a synthetic corticosteroid derived from fluticasone as a selective high affinity glucocorticoid agonist, MRP4 inhibitor;