Chelerythrine chloride - CAS 34316-15-9
Catalog number:
B0084-190109
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H18NO4+
Molecular Weight:
348.378
COA:
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Description:
Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable protein kinase C inhibitor. It is also the major active natural product found in the plant Zanthoxylum clava-herculis, exhibiting anti-bacterial activity against Staphylococcus aureus.
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B0084-190109 50 mg $198 In stock
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Brife Description:
cell-permeable protein kinase C inhibitor, Staphylococcus aureus
Synonyms:
Chelerythrine; Toddalin; EINECS 251-930-0; UNII-E3B045W6X0
MSDS:
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Application:
antibacterial agent
InChIKey:
LLEJIEBFSOEYIV-UHFFFAOYSA-N
InChI:
InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1
Canonical SMILES:
C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5
1.Chelerythrine delayed tumor growth and increased survival duration of Dalton's lymphoma bearing BALB/c H (2d) mice by activation of NK cells in vivo.
Kumar S, Tomar MS, Acharya A1. J Cancer Res Ther. 2015 Oct-Dec;11(4):904-10. doi: 10.4103/0973-1482.143342.
AIM: The aims of the present investigation were to evaluate the antitumor effect of chelerythrine (CHE) on in vivo growth and survival duration of BALB/c (H 2d ) mice bearing Dalton's lymphoma (DL) and enhanced function of tumor associated NK cells (TANK cells).
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CAS 34316-15-9 Chelerythrine chloride

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