CH5137291 - CAS 1043446-39-4
Catalog number:
1043446-39-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H14F3N5O3S2
Molecular Weight:
469.46
COA:
Inquire
Targets:
Androgen Receptor
Description:
CH5137291 is a potent androgen receptor (AR) pure antagonist which did not produce the agonist metabolite with AR nuclear translocation-inhibiting activity. It inhibits the growth of castration-resistant prostate cancer cells. It offers a novel therapeutic approach against major types of castration-resistant prostate cancers.
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Purity:
>98 %
Appearance:
Solid powder
Synonyms:
CH-5137291;6-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)pyridine-2-sulfonamide
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
CH5137291 offers a novel therapeutic approach against major types of castration-resistant prostate cancers.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Boiling Point:
654.4±65.0 °C | Condition: Press: 760 Torr
Density:
1.65±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
JIIHFLNYGVNTFP-UHFFFAOYSA-N
InChI:
InChI=1S/C18H14F3N5O3S2/c1-17(2)15(27)25(11-7-6-10(9-22)12(8-11)18(19,20)21)16(30)26(17)13-4-3-5-14(24-13)31(23,28)29/h3-8H,1-2H3,(H2,23,28,29)
Canonical SMILES:
CC1(C(=O)N(C(=S)N1C2=NC(=CC=C2)S(=O)(=O)N)C3=CC(=C(C=C3)C#N)C(F)(F)F)C
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