|Description||CH5132799 is a novel class I PI3K inhibitor, which exhibited a strong inhibitory activity especially against PI3K; (IC(50)=0.014 uM). In human tumor cell lines with PI3K pathway activation, CH5132799 showed potent antiproliferative activity. CH5132799 is orally available and showed significant antitumor activity in PI3K pathway-activated human cancer xenograft models in mice.|
|Synonyms||CH5132799; CH-5132799; CH 5132799|
|Current Developer||Chugai Pharmaceutical Co., Ltd|
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