Cgp 6809 - CAS 84069-38-5
Catalog number:
84069-38-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C12H23N3O7
Molecular Weight:
321.33
COA:
Inquire
Targets:
DNA Alkylator/Crosslinker
Description:
Cgp 6809 is a new methylnitrosoureido-sugar derivative. It is active against a broad spectrum of transplantable tumours in mice and rats. But Phase I clinical trials for the treatment of solid tumor were discontinued.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
ethyl-6-deoxy-3,5-di-O-methyl-6-(3-methyl-3-nitrosoureido)glucofuranoside
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
Cancer
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
DRYAELVKAAODIB-ILAIQSSSSA-N
InChI:
1S/C12H23N3O7/c1-5-21-11-8(16)10(20-4)9(22-11)7(19-3)6-13-12(17)15(2)14-18/h7-11,16H,5-6H2,1-4H3,(H,13,17)/t7-,8-,9-,10-,11+/m1/s1
Canonical SMILES:
O([C@@H]([C@@H]1[C@H](OC)[C@@H](O)[C@H](O1)OCC)CNC(N(N=O)C)=O)C
Current Developer:
Originator Novartis
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related DNA Alkylator/Crosslinker Products


CAS 41575-94-4 Carboplatin

Carboplatin
(CAS: 41575-94-4)

Carboplatin is a DNA synthesis inhibitor by binding to DNA and interfering with the cell's repair mechanism.

CAS 645-05-6 Altretamine

Altretamine
(CAS: 645-05-6)

Altretamine is an anti-neoplastic agent.

CAS 13010-47-4 Lomustine

Lomustine
(CAS: 13010-47-4)

Lomustine (420 μM) triggers apoptosis through the mitochondrial pathway via decrease in the level of the anti-apoptosis proteins Bcl-2 and Bcl-xl, respectively.

CAS 85622-93-1 Temozolomide

Temozolomide
(CAS: 85622-93-1)

Temozolomide is an oral chemotherapy drug.The therapeutic benefit of temozolomide depends on its ability to alkylate/methylate DNA, which most often occurs at t...

CAS 18883-66-4 Streptozotocin

Streptozotocin
(CAS: 18883-66-4)

Streptozotocin is a glucosamine-nitrosourea derivative, which is a methylating, carcinogenic, antibiotic and diabetes inducing agent. It is commonly used for th...

CAS 55-98-1 Busulfan

Busulfan
(CAS: 55-98-1)

Busulfan is a cell cycle non-specific alkylating antineoplastic agent.

CAS 23261-20-3 VAL-083

VAL-083
(CAS: 23261-20-3)

VAL-083 is a bi-functional alkylating agent; inhibit U251 and SF188 cell growth in monolayer better than TMZ and caused apoptosis.

CAS 154-93-8 Carmustine

Carmustine
(CAS: 154-93-8)

Carmustine is  antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA fun...

CAS 232931-57-6 SJG-136

SJG-136
(CAS: 232931-57-6)

SJG136 is a pyrrolobenzodiazepine dimer with potential antineoplastic activity. SJG-136 binds to the minor groove of DNA and induces interstrand cross-links bet...

CAS 129580-63-8 Satraplatin

Satraplatin
(CAS: 129580-63-8)

Satraplatin, also known as JM216, is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who ha...

CAS 50-18-0 Cyclophosphamide

Cyclophosphamide
(CAS: 50-18-0)

Low-dose preferentially deplets Treg cells; An alkylating agent of the nitrogen mustard type with antineoplastic and immunosuppressive activities; Phase I–II

CAS 3778-73-2 Ifosfamide

Ifosfamide
(CAS: 3778-73-2)

Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer.

CAS 299-75-2 Treosulfan

Treosulfan
(CAS: 299-75-2)

Treosulfan is the prodrug of a bifunctional sulfonate alkylating agent with myeloablative, immunosuppresive, and antineoplastic activities. Under physiological ...

Cgp 6809
(CAS: 84069-38-5)

Cgp 6809 is a new methylnitrosoureido-sugar derivative. It is active against a broad spectrum of transplantable tumours in mice and rats. But Phase I clinical t...

Altretamine hydrochloride
(CAS: 2975-00-0)

Altretamine hydrochloride, also called as hexamethylmelamine hydrochloride, is an alkylating agent with apparently less toxicity compared to other cytotoxic dru...

CAS 92118-27-9 Fotemustine

Fotemustine
(CAS: 92118-27-9)

Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of gu...

CAS 15663-27-1 Cisplatin

Cisplatin
(CAS: 15663-27-1)

Cisplatin induces cytotoxic by interaction with DNA to form DNA adducts which activate several signal transduction pathways, including Erk, p53, p73, and MAPK, ...

CAS 61825-94-3 Oxaliplatin

Oxaliplatin
(CAS: 61825-94-3)

Oxaliplatin is a platinum-based antineoplastic agent used in cancer chemotherapy that inhibits DNA synthesis by conforming DNA adducts in cancer cells.

CAS 31645-39-3 Palifosfamide

Palifosfamide
(CAS: 31645-39-3)

Palifosfamide is a synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide covalently linked to the amino acid lys...

Quick Inquiry

Verification code

Featured Items