CGP 52432 - CAS 139667-74-6
Catalog number: 139667-74-6
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H24Cl2NO4P
Molecular Weight:
384.24
COA:
Inquire
Targets:
GABA Receptor
Description:
CGP52432 is a potent and selective GABAB receptor antagonist with IC50 value of 85 nM.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98 %
Appearance:
White solid
Synonyms:
CGP 52432;3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid
Solubility:
H2O: soluble1 mg/mL, clear (warmed)
Storage:
-20°C Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
GJZVQXWEIYRHBE-UHFFFAOYSA-N
InChI:
1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)
Canonical SMILES:
O=[P@@](O)(C(OCC)OCC)CCCNCc1cc(c(cc1)Cl)Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related GABA Receptor Products


BAR-501
(CAS: 1632118-69-4)

BAR-501, a UDCA derivative, is a selective GPBAR1 agonist devoid of any FXR agonistic activity. BAR-501 effectively transactivates GPBAR1 in HEK293 cells overex...

CGP 54626 hydrochloride
(CAS: 149184-21-4)

The hydrochloride salt form of CGP 54626, a dichloropheny derivative, has been found to be a GABAB receptor antagonist that could probably be effective as an an...

TPA023
(CAS: 252977-51-8)

TPA023, also called as MK-0777, is a subtype-selective, mixed agonist-antagonist at GABAA receptor with anxiolytic and anticonvulsant effects.

CAS 123691-29-2 CGP 36216 hydrochloride

CGP 36216 hydrochloride
(CAS: 123691-29-2)

CGP 36216 hydrochloride is a selective GABAB antagonist that is active to presynaptic receptors but inactive to postsynaptic receptors.

CAS 104104-50-9 SR 95531 hydrobromide

SR 95531 hydrobromide
(CAS: 104104-50-9)

SR 95531 hydrobromide is a competitive GABAA receptor antagonist. SR 95531 differs from bicuculline that it selectively antagonizes GABA-induced Cl- currents bu...

CAS 125-33-7 Primidone

Primidone
(CAS: 125-33-7)

Primidone, a pyrimidinedione derivative, could be used as an anticonvulsant agent especially against epilepsy unspecified.

CAS 130477-52-0 L-655,708

L-655,708
(CAS: 130477-52-0)

L-655,708, an inverse agonist of α5 subunit involved in GABAA receptor, has been found to exhibit cognitive performance improvement in biological studies.

CAS 62666-20-0 Progabide

Progabide
(CAS: 62666-20-0)

Progabide is a gamma-aminobutyric acid (GABA) antagonist. It has agonistic activity for both the GABAA and GABAB receptors. It has antiepileptic activity and is...

CAS 99632-94-7 Ro 19-4603

Ro 19-4603
(CAS: 99632-94-7)

Ro 19-4603 is a novel potent partial inverse agonist of benzodiazepine (BZ) receptors. Ro19-4603 binds with high affinity to both diazepam-sensitive (DS) and di...

CAS 951650-22-9 NS 11394

NS 11394
(CAS: 951650-22-9)

NS 11394 is a drug with selectivity for the α3 and α5 subtypes. It acts as a subtype-selective positive allosteric modulator at GABAA receptors. It is used as a...

CAS 73604-30-5 (-)-Bicuculline methobromide

(-)-Bicuculline methobromide
(CAS: 73604-30-5)

(-)-Bicuculline methobromide is the methobromide salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors.

CAS 286456-42-6 L-838,417

L-838,417
(CAS: 286456-42-6)

L-838,417 is a subtype-selective GABAA receptor partial agonist. It selectively binds to α2, α3 and α5 subunits with Ki values of 0.67, 0.67 and 2.25 nM respect...

CAS 142720-24-9 FGIN-1-27

FGIN-1-27
(CAS: 142720-24-9)

FGIN-1-27 is a high affinity agonist of mitochondrial benzodiazepine receptors (PBR) binding to benzodiazepine receptors on mitochondrial membranes. FGIN-1-27 i...

SCH-50911
(CAS: 733717-87-8)

CH-50911 is a selective GABA-B antagonist with IC50 value of 1.1 μM. It is developed by Schering-Plough Corporation. CH-50911 is often used in pharmacology rese...

CAS 125464-42-8 Saclofen

Saclofen
(CAS: 125464-42-8)

Saclofen is a selective antagonist at GABAB receptors.

CAS 38090-53-8 TACA

TACA
(CAS: 38090-53-8)

TACA, the trans-isomer of CACA, is a potent GABAA and GABAC agonist, GABA uptake inhibitor and substrate for GABA-T. It also acts as a GABAA-ρ agonist.

CAS 145040-29-5 FGIN-1-43

FGIN-1-43
(CAS: 145040-29-5)

FGIN-1-43 is a potent and specific ligand for the mitochondial DBI receptor (MDR).

CAS 1758-80-1 L-DABA

L-DABA
(CAS: 1758-80-1)

L-DABA, (L-2,4-Diaminobutyric acid) is a noncompetitive GABA transaminase inhibitor (IC50> 500 μM) with antitumor activity in vivo and in vitro.

CAS 945828-50-2 AA 29504

AA 29504
(CAS: 945828-50-2)

AA 29504 is a positive allosteric modulator of GABAA receptors with anxiolytic activity. It modulates both α4β3δ-containing extrasynaptic receptors and α1β3γ2S-...

CAS 123690-79-9 CGP 35348

CGP 35348
(CAS: 123690-79-9)

CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynapti...

Quick Inquiry

Verification code

Featured Items