|Description||Cgp 39653 is a competitive N-Methyl-D-aspartate (NMDA) receptor antagonist. CGP 39653 can selectively bins to the NMDA receptor as an antagonist with high affinity. It is currently the ligand of choice for labeling the NMDA receptor.|
|Solubility||Soluble in DMSO|
|Application||the ligand of choice for labeling the NMDA receptor.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist (IC50 = 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes, respect...
DNQX disodium salt
The sodium salt form of DNQX, which is a selective non-NMDA receptor antagonist and could probably be useful in the treatment of Alzheimer's disease.
GV-196771, an indole derivative, has been found to be a non-opioid analgesic agent which is also a NMDA antagonist binds to glycine-binding site and was once st...
(R)-CPP, a piperazine derivative, has been found to be an effective NMDA receptor antagonist.
AM-36 is a potent blocker of batrachotoxinin (BTX)-sensitive Na+ channel binding in rat brain homogenates with an IC50 of 0.28 microM. As a unique neuroprotecti...
Indantadol is a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain.
IPAG is a potent NMDA receptor antagonist at σ sites. It was used as an old antipsychiatric.
5,7-Dichlorokynurenic acid sodium salt
The sodium salt form of 5,7-Dichlorokynurenic acid, which is an effective antagonist at the glycine site of the NMDA receptor.
Cerestat, a naphthalenyl-guanidine derivative, which has been found to be a potent and noncompetitive NMDA receptor antagonist(IC50 = 36 nM) and exhibits more t...
DL-AP5, an NMDA receptor antagonist, could be used as an anticonvulsant agent.
Quinolinic acid is an endogenous NMDA agonist and transmitter candidate. It may distinguish between NMDA receptor subtypes. By overactivating NMDA receptors, qu...
Radiprodil is a orally active and selective NMDA NR2B antagonist with a potential therapeutic agent in treatment of neuropathic pain and possibly other chronic ...
cis-ACPD has been found to be a potent NMDA receptor agonist as well as a mGluR agonist.
The hydrate of Felbamate which is an effective anticonvulsant agent. It was found to be clinically active for probably restraining the effectivity of NMDA.
(S)-(-)-HA-96 is an NMDA antagonist/partial agonist and possesses potent sedative and ataxic action. It causes disruption of striatal dopaminergic mechanisms.
Gavestinel is a non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM), display...
L-AP5 has been found to be an NMDA antagonist as well as a quisqualate-sensitized AP6 site agonist.
Mephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant.
Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia.