|Description||Cgp 39653 is a competitive N-Methyl-D-aspartate (NMDA) receptor antagonist. CGP 39653 can selectively bins to the NMDA receptor as an antagonist with high affinity. It is currently the ligand of choice for labeling the NMDA receptor.|
|Solubility||Soluble in DMSO|
|Application||the ligand of choice for labeling the NMDA receptor.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
Dioxadrol hydrochloride has been found to be an NMDA antagonist and is used as a dissociative anaesthetic drug. It produces similar effects to PCP in animals. I...
LY 257883, also known as PPPA, is a competitive NMDA receptor antagonist which displays moderate selectivity for NR2A-containing receptors. Ki values are 0.13μM...
Besonprodil, a benzimidazolone bioisostere, is an NMDA antagonist that selective for the NR2B subunit.
AM-36 is a potent blocker of batrachotoxinin (BTX)-sensitive Na+ channel binding in rat brain homogenates with an IC50 of 0.28 microM. As a unique neuroprotecti...
NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NM...
Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding...
Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
Dextromethorphan is an approved drug with sedative, dissociative, and stimulant properties. It is a cough suppressant in many over-the-counter cold and cough me...
Radiprodil is a orally active and selective NMDA NR2B antagonist with a potential therapeutic agent in treatment of neuropathic pain and possibly other chronic ...
LY 233536 is a novel competitive N-methyl-D-aspartate (NMDA) receptor antagonist, but few detailed information has been published yet.
LY 235959 is a competitive N-Methyl-D-Aspartate Receptor antagonist originated by Eli Lilly. No development was reported for treatment of Movement disorders in ...
Co 101244 hydrochloride
Co 101244 hydrochloride, with strongly neuroprotective effect in vivo and in vitro, is an ifenprodil-like noncompetitive, highly selective antagonist of NR2B-co...
The hydrate of Felbamate which is an effective anticonvulsant agent. It was found to be clinically active for probably restraining the effectivity of NMDA.
CGP 43487 has been found to be a NMDA receptor antagonist and was once studied about its influenment of dopaminergic function as a supplement in the treatment o...
Lanicemine, also know as AZD6765, has been to be a NMDA receptor antagonist that was once studiedd as a neuroprotective agent which was discontinued in 2007 and...
Mephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant.
ZL006 is a potent inhibitor of nNOS/PSD-95 interaction. And in mice subjected to mCao and reperfusion, pretreatment with Zl006 attenuated the ischemia-induced i...
Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia.
IC87201, an efficient inhibitor of PSD95-nNOS protein-protein interactions, was found by screening and shown to disrupt the nNOS/PSD-95 interaction in an in vit...
Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism o...