CGH 2466 dihydrochloride - CAS 1177618-54-0
Category: Inhibitor
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Molecular Formula:
C14H9N3SCl2.2HCl
Molecular Weight:
395.13
COA:
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Targets:
Adenosine A2b | Adenosine Receptor
Description:
CGH 2466 dihydrochloride is an adenosine A1, A2B and A3 receptor antagonist (IC50 = 19, 21, and 80 nM, respectively). It also displays an inhibitory effect on p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 is potentially used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Brife Description:
adenosine A1, A2B and A3 receptor antagonist
Purity:
≥99% by HPLC
Synonyms:
CGH 2466 dihydrochloride; CGH2466 dihydrochloride; CGH-2466 dihydrochloride; 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride
MSDS:
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Application:
potential treatment of asthma and COPD
InChIKey:
WHXRCTIBFLXKFD-UHFFFAOYSA-N
InChI:
InChI=1S/C14H9Cl2N3S.2ClH/c15-10-2-1-9(7-11(10)16)12-13(20-14(17)19-12)8-3-5-18-6-4-8;;/h1-7H,(H2,17,19);2*1H
Canonical SMILES:
C1=CC(=C(C=C1C2=C(SC(=N2)N)C3=CC=NC=C3)Cl)Cl.Cl.Cl
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Chemical Structure

CAS 1177618-54-0 CGH 2466 dihydrochloride

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