|Description||CFI-400945 is a PLK4 (polo-like kinase 4) inhibitor with potential antineoplastic activity originated by University Health Network. It can selectively inhibit PLK4, which leads to the disruption of mitosis and the induction of apoptosis. Phase I clinical trials for the treatment of solid tumor is on-going.|
|Synonyms||AK173721; SCHEMBL9946383; AKOS025396133;(2'S,3R)-2'-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5-methoxyspiro[1H-indole-3,1'-cyclopropane]-2-one;1616420-30-4 (CFI-400945 fumarate)|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||University Health Network|
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