|Description||CFI-400936 is a selective proteine kinase TTK inhibitor with IC50 value of 3.6nM. It demonstrates good activity in cell based assay and selectivity against a panel of human kinases. CFI-400936 shows potential anticancer activity.|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
N-Desmethyl Regorafenib is a metabolite of Regorafenib. Regorafenib is useful for the treatment of inflammation and as an anti-proliferative agent.
An inhibitor of 5α-reductase
DS-1040 inhibits the activated form of thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). DS-1040 subst...
Mecarbinate is a chemical intermediate of arbidol hydrochloride.
DZ2002 is a potent and reversible S-Adenosyl-L-homocysteine Hydrolase(SAHH; AdoHcy Hydrolase) inhibitor with Ki of 17.9 nM.
S107 is a type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. S107 increased FKBP12 binding to RyR1 in...
Osthol is an is a calcium channel blocker, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.
Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female ...
Sortin1 is a synthetic chemical ats as a Sorting inhibitor, redirecting the vacuolar destination of plant carboxypeptidase Y and other proteins in Arabidopsis.
Menadione shows vitamin K activity, used as a nutritional supplement.
NADP disodium salt
NADP disodium salt, also called as Coenzyme II, widely distributed in living matter, is a participant coenzyme in aerobic and anaerobic oxidations.
Atagabalin, also referred to PD-0200,390, is a gabamimetic agent developed as a treatment for insomnia but was discontinued following unsatisfactory trial resul...
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Ombrabulin hydrochloride is the hydrochloride salt form of Ombrabulin. Ombrabulin, also called as AVE8062, a synthetic water-soluble analogue of CA-4-P, binds t...
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ISA-2011B is a Phosphatidylinositol-4-phosphate 5-kinase-α (PIP5Kα) inhibitor. Research shows that the overexpression of PIP5K1α is associated with poor prognos...
PF-1355 is a selective, mechanism-based inhibitor of myeloperoxidase (MPO) (IC50 = 1.5 μM in LPS-stimulated human whole blood) with excellent selectivity for MP...