|Description||Cevimeline hydrochloride is a selective M1 receptor agonist.|
Propantheline Bromide is an antimuscarinic agent used as an antispasmodic for the treatment of ulcers.
Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
Glycopyrrolate bromide is a muscarinic competitive antagonist used as an antispasmodic.
Atropine sulfate salt monohydrate
Atropine is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.
Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor...
Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 1...
YM-46303 is an mAChR antagonist which had a binding affinity of 0.39 nM to M3-receptors. YM-46303 exhibits the highest affinities for M1 and M3 receptors. YM-46...
Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...
Mepenzolate Bromide is a muscarinic antagonist used to treat gastrointestinal disorders, and decreases the severity of elastase-induced airspace enlargement and...
Tiotropium Bromide hydrate
Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a mus...
Alvameline, also known as Lu25-109, is a partial M1agonist and M2/M3antagonist that was progressed into clinical studies for the treatment of Alzheimer's diseas...
This active molecular is a muscarinic agonist agent.
PF-06767832 is a cell permeable, potent and selective M1 muscarinic acetylcholine receptor Positive Allosteric Modulator (PAM).
VU 0029767 is a positive allosteric modulator of M1, a member of the muscarinic acetylcholine family of GPCRs (mAChRs). VU 0029767 enhances the competitive effe...
VU 6008667 is a selective negative allosteric modulator (NAM) of M5 muscarinic acetylcholine receptor (mAChR) (IC50 values of 1.2 and 1.6 μM in human and rat M5...
BQCA is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR), as it dose-dependently reduces the concentration o...
Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor- and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively.
Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki=0.19 nM), ~200 fold selectivity over M2 receptor.
5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladde...
Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. It is used for the adjunctive treatment of all forms of Park...