Cetirizine diHCl - CAS 83881-52-1
Catalog number:
83881-52-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H26Cl2N2O3
Molecular Weight:
425.35
COA:
Inquire
Targets:
Histamine Receptor
Description:
Cetirizine is a major metabolite of hydroxyzine, and a racemic selective H1 receptor antagonist.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Synonyms:
Vitamin B2
MSDS:
Inquire
1.Suppression of histamine-induced skin reactions by loratadine and cetirizine diHCl.
Kontou-Fili K1, Paleologos G, Herakleous M. Eur J Clin Pharmacol. 1989;36(6):617-9.
The skin reactivity to histamine was measured in 10 healthy and 10 atopic subjects after the ingestion of single doses of loratadine 10 mg, cetirizine diHCl 10 mg and placebo, in a double-blind cross-over randomized study. The anti-H1 effect of cetirizine diHCl proved to be significantly more rapid, more pronounced and longer lasting than that of loratadine.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Histamine Receptor Products


UR-PI376
(CAS: 1192559-94-6)

This active molecular is a imidazolylpropylguanidine type compound as a hH4R agonist (histamine H4 receptor agonist) showing negligible hH1R and hH2R activities...

CAS 79794-75-5 Loratadine

Loratadine
(CAS: 79794-75-5)

Loratadine is a histamine H1 receptor antagonist, used to treat allergies. It also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.

CAS 13073-96-6 Decloxizine hydrochloride

Decloxizine hydrochloride
(CAS: 13073-96-6)

The hydrochloride salt form of Decloxizine, a hydroxyzine analogue, is a histamine 1 receptor antagonist and often known as an impurity of Hydroxyzine.

CAS 154-69-8 Tripelennamine hydrochloride

Tripelennamine hydrochloride
(CAS: 154-69-8)

Tripelennamine hydrochloride, the hydrochloride salt form of tripelennamine, is a blood-brain barrier penetrant and orally active H1-receptor antagonist. Tripel...

CAS 5636-83-9 Dimethindene

Dimethindene
(CAS: 5636-83-9)

Dimethindene is a selective histamine H1 antagonist. It binds to the histamine H1 receptor. It is an antiallergic drug and is used in hypersensitivity reactions...

CAS 93793-83-0 Roxatidine Acetate HCl

Roxatidine Acetate HCl
(CAS: 93793-83-0)

Roxatidine Acetate HCl is a specific and competitive histamin H2 receptor antagonist.

CAS 100299-08-9 Pemirolast potassium

Pemirolast potassium
(CAS: 100299-08-9)

Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.

CAS 51481-61-9 Cimetidine

Cimetidine
(CAS: 51481-61-9)

Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.

CAS 66357-59-3 Ranitidine

Ranitidine
(CAS: 66357-59-3)

Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in treatment of peptic ulcer disease and gastroesoph...

CAS 99291-25-5 Levodropropizine

Levodropropizine
(CAS: 99291-25-5)

Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory n...

CAS 523-87-5 Dramamine

Dramamine
(CAS: 523-87-5)

Dimenhydrinate is an over-the-counter antiemetic used to prevent nausea and motion sicknes composed of 8-Chlorotheophylline and Diphenhydramine.

CAS 108498-50-6 FRG8701

FRG8701
(CAS: 108498-50-6)

FRG-8701 is a novel Histamine H2 receptor antagonist (IC50= 0.25~ 0.43 μM). FRG-8701 has relatively long-lasting antisecretory ef fects in comparison with famot...

LY-150310
(CAS: 103294-47-9)

LY-150310 is a histamine H1-receptor antagonist. It could alter prostanoid concentrations in vitro and in vivo.

CAS 13461-01-3 aceprometazine

aceprometazine
(CAS: 13461-01-3)

Aceprometazine is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders su...

CAS 68-88-2 Hydroxyzine

Hydroxyzine
(CAS: 68-88-2)

Hydroxyzine is a histamine H1-receptor antagonist.

CAS 1104-22-9 Meclizine 2HCl

Meclizine 2HCl
(CAS: 1104-22-9)

Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation...

CAS 84-96-8 Trimeprazine

Trimeprazine
(CAS: 84-96-8)

Alimemazine is a phenothiazine derivative as a Histamine Receptor antagonist. It can be used as an antipruritic . It also acts as a sedative, hypnotic, and anti...

CAS 5579-84-0 Betahistine dihydrochloride

Betahistine dihydrochloride
(CAS: 5579-84-0)

Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 μM.

CAS 64-89-1 Propiomazine Hydrochloride

Propiomazine Hydrochloride
(CAS: 64-89-1)

Propiomazine Hydrochloride is an antihistamine blocking H1 receptors. It is used to treat insomnia and to produce drowsiness. It is also used to relieve anxiety...

CAS 929622-08-2 Bavisant

Bavisant
(CAS: 929622-08-2)

Bavisant is a highly selective, orally active antagonist of the human H3 receptor. It is a novel mechanism of action, involving wakefulness and cognition. It ha...

Chemical Structure

CAS 83881-52-1 Cetirizine diHCl

Quick Inquiry

Verification code

Featured Items