Cephalothin sodium - CAS 58-71-9
Catalog number: 58-71-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H15N2NaO6S2
Molecular Weight:
418.41
COA:
Inquire
Targets:
Antibacterial
Description:
Cephalothin sodium is a semisynthetic first generation cephalosporin having a broad spectrum of antibiotic activity that is administered parenterally used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or join
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Purity:
≥98%
Appearance:
White to Off-White Solid
Synonyms:
7-(Thiophene-2-acetamido)cephalosporanic acid sodium; sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or joints, respiratory tract, skin, and urinary tract.
Quality Standard:
Enterprise Standard/EP/USP
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Melting Point:
>163 °C
InChIKey:
VUFGUVLLDPOSBC-XRZFDKQNSA-M
InChI:
1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1
Canonical SMILES:
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
Current Developer:
Eli Lilly Canada Inc
1.In vitro and in vivo laboratory evaluation of cephalothin, a new broad spectrum antibiotic.
BONIECE WS, WICK WE, HOLMES DH, REDMAN CE. J Bacteriol. 1962 Dec;84:1292-6.
Boniece, W. S. (Lilly Research Laboratories, Indianapolis, Indiana), W. E. Wick, D. H. Holmes, and C. E. Redman. In vitro and in vivo laboratory evaluation of cephalothin, a new broad-spectrum antibiotic. J. Bacteriol. 84:1292-1296. 1962.-Cephalothin, a new cephalosporin antibiotic, is the sodium salt of 7-(thiophene-2-acetamido) cephalosporanic acid. The activity of this antibiotic against a variety of gram-positive and gram-negative bacteria is described, as determined by the tube-dilution and disc-plate methods. Correlations of the results of the therapy of experimental infections in mice with in vitro sensitivity to cephalothin are presented. The data from the gram-negative bacterial infection tests suggest the following relationship on a within strain basis: ed(50) = C(i)ld(50) (bi), where the subscript i stands for the various strains.
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CAS 58-71-9 Cephalothin sodium

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