Cephalothin sodium - CAS 58-71-9
Catalog number: 58-71-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H15N2NaO6S2
Molecular Weight:
418.41
COA:
Inquire
Targets:
Antibacterial
Description:
Cephalothin sodium is a semisynthetic first generation cephalosporin having a broad spectrum of antibiotic activity that is administered parenterally used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or join
Purity:
≥98%
Appearance:
White to Off-White Solid
Synonyms:
7-(Thiophene-2-acetamido)cephalosporanic acid sodium; sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or joints, respiratory tract, skin, and urinary tract.
Quality Standard:
Enterprise Standard/EP/USP
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Melting Point:
>163 °C
InChIKey:
VUFGUVLLDPOSBC-XRZFDKQNSA-M
InChI:
1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1
Canonical SMILES:
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
Current Developer:
Eli Lilly Canada Inc
1.In vitro and in vivo laboratory evaluation of cephalothin, a new broad spectrum antibiotic.
BONIECE WS, WICK WE, HOLMES DH, REDMAN CE. J Bacteriol. 1962 Dec;84:1292-6.
Boniece, W. S. (Lilly Research Laboratories, Indianapolis, Indiana), W. E. Wick, D. H. Holmes, and C. E. Redman. In vitro and in vivo laboratory evaluation of cephalothin, a new broad-spectrum antibiotic. J. Bacteriol. 84:1292-1296. 1962.-Cephalothin, a new cephalosporin antibiotic, is the sodium salt of 7-(thiophene-2-acetamido) cephalosporanic acid. The activity of this antibiotic against a variety of gram-positive and gram-negative bacteria is described, as determined by the tube-dilution and disc-plate methods. Correlations of the results of the therapy of experimental infections in mice with in vitro sensitivity to cephalothin are presented. The data from the gram-negative bacterial infection tests suggest the following relationship on a within strain basis: ed(50) = C(i)ld(50) (bi), where the subscript i stands for the various strains.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Antibacterial Products


CAS 723-46-6 Sulfamethoxazole

Sulfamethoxazole
(CAS: 723-46-6)

Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.

CAS 104376-79-6 Ceftriaxone sodium hydrate (2:4:7)

Ceftriaxone sodium hydrate (2:4:7)
(CAS: 104376-79-6)

Ceftriaxone sodium hydrate is a third-generation cephalosporin antibiotic.

CAS 179033-51-3 Timcodar

Timcodar
(CAS: 179033-51-3)

Timcodar, a pyridine derivative, has been found to be a p-glycoprotein inhibitor as well as nerve growth factor stimulant and was once studied in the treatment ...

CAS 165800-03-3 Linezolid

Linezolid
(CAS: 165800-03-3)

Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli.

CAS 163680-77-1 Pazufloxaxin methanesulfonate

Pazufloxaxin methanesulfonate
(CAS: 163680-77-1)

Pazufloxaxin methanesulfonate is a fluoroquinolone broad-spectrum antibacterial which potent actions against both gram-positive and gram-negative bacteria.

N-Acetyl-Calicheamicin
(CAS: 108212-76-6)

N-Acetyl-Calicheamicin, a derivative of Calicheamicin, is a member of enediyne antitumor antibiotics that could be a potential cytotoxic DNA-binding agent.

CAS 39831-55-5 Amikacin disulfate

Amikacin disulfate
(CAS: 39831-55-5)

Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.

ABT-255 Hcl
(CAS: 181141-52-6)

ABT-255, a novel 2-pyridone antibacterial agent, is an analog of ABT-719 with improvements in the therapeutic margin against common gram-positive and -negative ...

CAS 405165-61-9 Besifloxacin Hydrochloride

Besifloxacin Hydrochloride
(CAS: 405165-61-9)

Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-ne...

CAS 127294-70-6 Balofloxacin

Balofloxacin
(CAS: 127294-70-6)

Balofloxacin is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.

CHIR-090
(CAS: 728865-23-4)

CHIR-090 is a very potent and tight-binding inhibitor of LpxC, which is a zinc-dependent amidase and present in almost all Gram-negative bacteria, and is a prom...

CAS 13614-98-7 Minocycline Hydrochloride

Minocycline Hydrochloride
(CAS: 13614-98-7)

Minocycline Hydrochlorideis the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA t...

CAS 86-42-0 AMODIAQUINE

AMODIAQUINE
(CAS: 86-42-0)

Amodiaquine is a drug which used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. It has similar action to chloroquine. It is not a...

CAS 101363-10-4 Rufloxacin

Rufloxacin
(CAS: 101363-10-4)

Rufloxacin, a quinolone derivative, is an antibiotic which could restrain the differentiation of B-cell and selectively act on DNA gyrase.

CAS 1404-93-9 Vancomycin HCl

Vancomycin HCl
(CAS: 1404-93-9)

Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.

CAS 651-06-9 Sulfameter

Sulfameter
(CAS: 651-06-9)

Sulfameter is a long-acting sulfonamide antibacterial. It is used as a leprostatic agent and in the treatment of urinary tract infections.

CAS 81103-11-9 Clarithromycin

Clarithromycin
(CAS: 81103-11-9)

Clarithromycin, a CYP3A4 inhibitor, is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of...

CAS 50370-12-2 Cefadroxil

Cefadroxil
(CAS: 50370-12-2)

Cefadroxilis a broad-spectrum antibiotic of the cephalosporin type as a first-generation cephalosporin antibiotic used to treat urinary tract infections

CAS 6209-17-2 Sulfacetamide sodium monohydrate

Sulfacetamide sodium monohydrate
(CAS: 6209-17-2)

Sulfacetamide sodium monohydrate is an antibiotic used to treat acne and seborrheic dermatitis.

CAS 4800-94-6 Carbenicillin disodium

Carbenicillin disodium
(CAS: 4800-94-6)

Carbenicillin is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity. The c...

Chemical Structure

CAS 58-71-9 Cephalothin sodium

Quick Inquiry

Verification code

Featured Items