Cephalothin sodium - CAS 58-71-9
Catalog number:
58-71-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H15N2NaO6S2
Molecular Weight:
418.41
COA:
Inquire
Targets:
Antibacterial
Description:
Cephalothin sodium is a semisynthetic first generation cephalosporin having a broad spectrum of antibiotic activity that is administered parenterally used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or join
Publictions citing BOC Sciences Products
  • >> More
Purity:
≥98%
Appearance:
White to Off-White Solid
Synonyms:
7-(Thiophene-2-acetamido)cephalosporanic acid sodium; sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or joints, respiratory tract, skin, and urinary tract.
Quality Standard:
Enterprise Standard/EP/USP
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Melting Point:
>163 °C
InChIKey:
VUFGUVLLDPOSBC-XRZFDKQNSA-M
InChI:
1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1
Canonical SMILES:
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
Current Developer:
Eli Lilly Canada Inc
1.In vitro and in vivo laboratory evaluation of cephalothin, a new broad spectrum antibiotic.
BONIECE WS, WICK WE, HOLMES DH, REDMAN CE. J Bacteriol. 1962 Dec;84:1292-6.
Boniece, W. S. (Lilly Research Laboratories, Indianapolis, Indiana), W. E. Wick, D. H. Holmes, and C. E. Redman. In vitro and in vivo laboratory evaluation of cephalothin, a new broad-spectrum antibiotic. J. Bacteriol. 84:1292-1296. 1962.-Cephalothin, a new cephalosporin antibiotic, is the sodium salt of 7-(thiophene-2-acetamido) cephalosporanic acid. The activity of this antibiotic against a variety of gram-positive and gram-negative bacteria is described, as determined by the tube-dilution and disc-plate methods. Correlations of the results of the therapy of experimental infections in mice with in vitro sensitivity to cephalothin are presented. The data from the gram-negative bacterial infection tests suggest the following relationship on a within strain basis: ed(50) = C(i)ld(50) (bi), where the subscript i stands for the various strains.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Antibacterial Products


CAS 163680-77-1 Pazufloxaxin methanesulfonate

Pazufloxaxin methanesulfonate
(CAS: 163680-77-1)

Pazufloxaxin methanesulfonate is a fluoroquinolone broad-spectrum antibacterial which potent actions against both gram-positive and gram-negative bacteria.

CAS 98-96-4 Pyrazinamide

Pyrazinamide
(CAS: 98-96-4)

Pyrazinamide is a pyrazine that is used therapeutically as an antitubercular agent. It is a prodrug that stops the growth of Mycobacterium tuberculosis. It was ...

LY 186826
(CAS: 126165-79-5)

LY 186826 is an antibacterial agent with bicyclic pyrazolidinones containing a novel aza-γ-lactam ring structure. The properties of this compound appear to be r...

Ribocil
(CAS: 1381289-58-2)

Ribocil, a newly developed riboswitches chemical modulator, could selectively restrain the expression of GFP and probably influence bacterial cell growth. IC50:...

LY 215890
(CAS: 153502-35-3)

LY 215890 has been found to have probable antibiotic activity.

CAS 1070-11-7 Ethambutol HCl

Ethambutol HCl
(CAS: 1070-11-7)

Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

CAS 773-76-2 Chloroxine

Chloroxine
(CAS: 773-76-2)

Chloroxine has bacteriostatic, fungistatic and antiprotozoal properties. It is effective against Streptococci, Staphylococci, Candida, Candida albicans, Shigell...

CAS 13009-99-9 Mafenide Acetate

Mafenide Acetate
(CAS: 13009-99-9)

Mafenide is a bacteriostatic antibiotic with a broad activity against Gram positive, Gram negative bacteria and Clostridia. Mafenide acetate penetrates eschar a...

CAS 74849-93-7 Cefpiramide sodium

Cefpiramide sodium
(CAS: 74849-93-7)

Cefpiramide sodium is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity. It was more active against Acinetobacter spp. and ...

CAS 3963-95-9 Methacycline Hydrochloride

Methacycline Hydrochloride
(CAS: 3963-95-9)

Methacycline HCl is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various...

CAS 194804-75-6 Garenoxacin

Garenoxacin
(CAS: 194804-75-6)

Garenoxacin, also called as BMS 284756, a new desfluoro(6)quinolone, is a topoisomerase II inhibitor with actibacterial activity to treat Gram-positive and Gram...

CAS 14769-73-4 Levamisole

Levamisole
(CAS: 14769-73-4)

Levamisole, a thiazole derivative, has been found to be an antibiotic used to against parasitic worm infections and could also have potential activity in antica...

CAS 65710-07-8 Apramycin Sulfate

Apramycin Sulfate
(CAS: 65710-07-8)

Apramycin is an aminoglycoside antibiotic. It acts by blocking translocation and binding also to the eukaryotic decoding site despite differences in key residue...

CAS 7177-50-6 Nafcillin Sodium

Nafcillin Sodium
(CAS: 7177-50-6)

Nafcillin sodium reversibly inhibits β-lactamase with Kd of 33 mM.

CAS 1257426-19-9 TBA-354

TBA-354
(CAS: 1257426-19-9)

TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamani...

CAS 34444-01-4 Cefamandole

Cefamandole
(CAS: 34444-01-4)

Cefamandole is is the formate ester cefamandole nafate, a second-generation broad-spectrum cephalosporin antibiotic. It releases free NMTT, which can cause hypo...

Finafloxacin
(CAS: 209342-40-5)

Finafloxacin is a pH-activated fluoroquinolone antimicrobial agent. Finafloxacin has an advantage over other fluoroquinolones as it shows optimal efficacy in sl...

CAS 110871-86-8 Sparfloxacin

Sparfloxacin
(CAS: 110871-86-8)

Sparfloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.

CAS 389139-89-3 Omadacycline

Omadacycline
(CAS: 389139-89-3)

Omadacycline is a new tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome.

CAS 526-08-9 Sulfaphenazole

Sulfaphenazole
(CAS: 526-08-9)

Sulfaphenazole is an inhibitor of CYP2C9 (Ki = 0.3 μM) acts as an antibacterial and antimicrobial.

Chemical Structure

CAS 58-71-9 Cephalothin sodium

Quick Inquiry

Verification code

Featured Items