|Description||Ceftriaxone is an antibiotic useful for the treatment of a number of bacterial infections. It inhibits bacterial cell wall synthesis by means of binding to the penicillin-binding proteins (PBPs) and has potential to manipulate glutamate transmission and ameliorate neurotoxicity.|
Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.
Moxifloxacin, a fourth-generation synthetic fluoroquinolone antibacterial agent used to treat a number of infections, including: respiratory tract infections, c...
LY 186826 is an antibacterial agent with bicyclic pyrazolidinones containing a novel aza-γ-lactam ring structure. The properties of this compound appear to be r...
Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and i...
TMC207 is a first-in-class diarylquinoline compound with a novel mechanism of action, the inhibition of bacterial ATP synthase, and potent activity against drug...
Tunicamycin, a mixture of homologous nucleoside antibiotics, has been used to study the effect of N-linked glycosylation of human proton-coupled folate transpor...
The mesylate salt form of alatrofloxacin, a fluoroquinolone derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed to be...
Marbofloxacin exhibits high bactericidal activity against a broad spectrum of aerobic Gram-negative and some Gram-positive bacteria, as well as Mycoplasma spp.
Fleroxacin is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV. Like other quinolones and fluoroquinolones, it eradicates bacteria by...
Sulfamethoxypyrazine, one of the sulfonamide antibiotcs, has been found to be effective against chronic bronchitis, malaria and urinary tract infections.
Oxytetracycline (Terramycin) was the second of the broad-spectrum tetracycline group of antibiotics to be discovered.
Balofloxacin is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.
A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide.
Levamisole, a thiazole derivative, has been found to be an antibiotic used to against parasitic worm infections and could also have potential activity in antica...
AU1235, an adamantyl urea derivative, is an inhibitor of Mycobacterium tuberculosis that was active on MDR strains and<br/>had a bactericidal effect on replicat...
Pazufloxacin (T-3761), a new quinolone derivative, showed broad and potent antibacterial activity. T-3761 showed good efficacy in mice against systemic, pulmona...
Cefpiramide sodium is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity. It was more active against Acinetobacter spp. and ...
Nithiamide is efficient in preventing and treating swine dysentery in experimentally inoculated pigs.
Apramycin stands out among aminoglycosides for its mechanism of action which is based on blocking translocation and its ability to bind also to the eukaryotic d...
Tylosin phosphate(Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms.